Prohibitions. As a material inducement to Landlord to enter into this Lease with Tenant, Tenant has fully and accurately completed Landlord’s Pre-Leasing Environmental Exposure Questionnaire (the "Environmental Questionnaire"), which is attached as Exhibit E. Tenant agrees that except for those chemicals or materials, and their respective quantities, specifically listed on the Environmental Questionnaire (as the same may be updated from time to time as provided below), neither Tenant nor Tenant’s employees, contractors and subcontractors of any tier, entities with a contractual relationship with Tenant (other than Landlord), or any entity acting as an agent or sub-agent of Tenant (collectively, "Tenant's Agents") will produce, use, store or generate any "Hazardous Materials," as that term is defined below, on, under or about the Premises, nor cause any Hazardous Material to be brought upon, placed, stored, manufactured, generated, blended, handled, recycled, used or "Released," as that term is defined below, on, in, under or about the Premises. If any information provided to Landlord by Tenant on the Environmental Questionnaire, or otherwise relating to information concerning Hazardous Materials is intentionally false, incomplete, or misleading in any material respect, the same shall be deemed a default by Tenant under this Lease. Upon Landlord's request, or in the event of any material change in Tenant's use of Hazardous Materials in the Premises, Tenant shall deliver to Landlord an updated Environmental Questionnaire at least once a year. Tenant shall notify Landlord prior to using any Hazardous Materials in the Premises not described on the initial Environmental Questionnaire, and, to the extent such use would, in Landlord's reasonable judgment, cause a material increase in the risk of liability compared to the uses previously allowed in the Premises, such additional use shall be subject to Landlord's prior consent, which may be withheld in Landlord’s reasonable discretion. Tenant shall not install or permit Tenant's Agents to install any underground storage tank on the Premises. For purposes of this Lease, "Hazardous Materials" means all flammable explosives, petroleum and petroleum products, waste oil, radon, radioactive materials, toxic pollutants, asbestos, polychlorinated biphenyls ("PCBs"), medical waste, chemicals known to cause cancer or reproductive toxicity, pollutants, contaminants, hazardous wastes, toxic substances or related materials, including without limitation any chemical, element, compound, mixture, solution, substance, object, waste or any combination thereof, which is or may be hazardous to human health, safety or to the environment due to its radioactivity, ignitability, corrosiveness, reactivity, explosiveness, toxicity, carcinogenicity, infectiousness or other harmful or potentially harmful properties or effects, or defined as, regulated as or included in, the definition of "hazardous substances," "hazardous wastes," "hazardous materials," or "toxic substances" under any Environmental Laws. For purposes of this Lease, "Release" or "Released" or "Releases" shall mean any release, deposit, discharge, emission, leaking, spilling, seeping, migrating, injecting, pumping, pouring, emptying, escaping, dumping, disposing, or other movement of Hazardous Materials into the environment. Landlord acknowledges that Tenant will be installing and using fume hoods in the Premises and that emissions of Hazardous Materials into the air in compliance with all Environmental Laws shall not be considered Releases.

Prohibitions. As a material inducement to Landlord to enter into this Lease with Tenant, Tenant has fully and accurately completed Landlord’s Pre-Leasing Environmental Exposure Questionnaire (the 1">"Environmental Questionnaire"1">“Environmental Questionnaire”), which is attached as Exhibit E. Tenant agrees that except for those chemicals or materials, and their 3">respective quantities, specifically3">approximate quantities listed on the Environmental Questionnaire (as the same may be updated from time to time as provided below)5">,5"> or any similar chemicals or materials used for substantially the same purposes in substitution thereof in compliance with applicable law, neither Tenant nor Tenant’s employees, contractors and subcontractors of any tier, entities with a contractual relationship with Tenant (other than Landlord), or any entity acting as an agent or sub-agent of Tenant (collectively, "Tenant's Agents") will produce, use, store or generate any "Hazardous Materials," as that term is defined below, on, under or about the Premises, nor cause any Hazardous Material to be brought upon, placed, stored, manufactured, generated, blended, handled, recycled, used or "Released," as that term is defined below, on, in, under or about the Premises. If any information provided to Landlord by Tenant on the Environmental Questionnaire, or otherwise relating to information concerning Hazardous Materials is intentionally false, incomplete, or misleading in any material respect, the same shall be deemed a default by Tenant under this Lease. Upon Landlord's 7">request,7">request (but no more than once each Lease Year), or in the event of any material change in Tenant's use of Hazardous Materials in the Premises, Tenant shall deliver to Landlord an updated Environmental 9">Questionnaire at least once a year.9">Questionnaire. Tenant shall notify Landlord prior to using any Hazardous Materials in the Premises not described on the initial Environmental Questionnaire, 11">and, to the extent11">and such13"> use would, in Landlord's reasonable judgment, cause a material increase in the risk of liability compared to the uses previously allowed in the Premises, such additional use shall be subject to 15">Landlord's prior consent, which may be withheld in Landlord’s reasonable discretion.15">all of the provisions of this Lease. Tenant shall not install or permit Tenant's Agents to install any underground storage tank on the Premises. For purposes of this Lease, "Hazardous Materials" means all flammable explosives, petroleum and petroleum products, waste oil, radon, radioactive materials, toxic pollutants, asbestos, polychlorinated biphenyls 17">("PCBs"17">(“PCBs”), medical waste, chemicals known to cause cancer or reproductive toxicity, pollutants, contaminants, hazardous wastes, toxic substances or related materials, including without limitation any chemical, element, compound, mixture, solution, substance, object, waste or any combination thereof, 19">which19">that is or may be hazardous to human health, safety or to the environment due to its radioactivity, ignitability, corrosiveness, reactivity, explosiveness, toxicity, carcinogenicity, infectiousness or other harmful or potentially harmful properties or effects, or defined as, regulated as or included in, the definition of 21">"hazardous21">“hazardous substances,23">" "hazardous23">” “hazardous wastes,25">" "hazardous25">” “hazardous materials,27">"27">” or 29">"toxic substances"29">“toxic substances” under any Environmental Laws. For purposes of this Lease, "Release" or "Released" or "Releases" shall mean any release, deposit, discharge, emission, leaking, spilling, seeping, migrating, injecting, pumping, pouring, emptying, escaping, dumping, disposing, or other movement of Hazardous Materials into the environment. Landlord acknowledges that Tenant will be installing and using fume hoods in the Premises and that emissions of Hazardous Materials into the air in compliance with all Environmental Laws shall not be considered Releases.

Prohibitions. As a material inducement to Landlord to enter into this Lease with Tenant, Tenant has fully and accurately completed Landlord’s Pre-Leasing Environmental Exposure Questionnaire (the 1">"Environmental Questionnaire"1">“Environmental Questionnaire”), which is attached as Exhibit E. Tenant agrees that except for those chemicals or materials, and their 3">respective quantities, specifically3">approximate quantities listed on the Environmental Questionnaire (as the same may be updated from time to time as provided below)5">,5"> or any similar chemicals or materials used for substantially the same purposes in substitution thereof in compliance with applicable law, neither Tenant nor Tenant’s employees, contractors and subcontractors of any tier, entities with a contractual relationship with Tenant (other than Landlord), or any entity acting as an agent or sub-agent of Tenant (collectively, "Tenant's Agents") will produce, use, store or generate any "Hazardous Materials," as that term is defined below, on, under or about the Premises, nor cause any Hazardous Material to be brought upon, placed, stored, manufactured, generated, blended, handled, recycled, used or "Released," as that term is defined below, on, in, under or about the Premises. If any information provided to Landlord by Tenant on the Environmental Questionnaire, or otherwise relating to information concerning Hazardous Materials is intentionally false, incomplete, or misleading in any material respect, the same shall be deemed a default by Tenant under this Lease. Upon Landlord's 7">request,7">request (but no more than once each Lease Year), or in the event of any material change in Tenant's use of Hazardous Materials in the Premises, Tenant shall deliver to Landlord an updated Environmental 9">Questionnaire at least once a year.9">Questionnaire. Tenant shall notify Landlord prior to using any Hazardous Materials in the Premises not described on the initial Environmental Questionnaire, 11">and, to the extent11">and such13"> use would, in Landlord's reasonable judgment, cause a material increase in the risk of liability compared to the uses previously allowed in the Premises, such additional use shall be subject to 15">Landlord's prior consent, which may be withheld in Landlord’s reasonable discretion.15">all of the provisions of this Lease. Tenant shall not install or permit Tenant's Agents to install any underground storage tank on the Premises. For purposes of this Lease, "Hazardous Materials" means all flammable explosives, petroleum and petroleum products, waste oil, radon, radioactive materials, toxic pollutants, asbestos, polychlorinated biphenyls 17">("PCBs"17">(“PCBs”), medical waste, chemicals known to cause cancer or reproductive toxicity, pollutants, contaminants, hazardous wastes, toxic substances or related materials, including without limitation any chemical, element, compound, mixture, solution, substance, object, waste or any combination thereof, 19">which19">that is or may be hazardous to human health, safety or to the environment due to its radioactivity, ignitability, corrosiveness, reactivity, explosiveness, toxicity, carcinogenicity, infectiousness or other harmful or potentially harmful properties or effects, or defined as, regulated as or included in, the definition of 21">"hazardous21">“hazardous substances,23">" "hazardous23">” “hazardous wastes,25">" "hazardous25">” “hazardous materials,27">"27">” or 29">"toxic substances"29">“toxic substances” under any Environmental Laws. For purposes of this Lease, "Release" or "Released" or "Releases" shall mean any release, deposit, discharge, emission, leaking, spilling, seeping, migrating, injecting, pumping, pouring, emptying, escaping, dumping, disposing, or other movement of Hazardous Materials into the environment. Landlord acknowledges that Tenant will be installing and using fume hoods in the Premises and that emissions of Hazardous Materials into the air in compliance with all Environmental Laws shall not be considered Releases.

Prohibitions. As a material inducement to Landlord to enter into this Lease with Tenant, Tenant has fully and accurately completed Landlord’s Pre-Leasing Environmental Exposure Questionnaire (the "Environmental Questionnaire"), which is attached as Exhibit E. Tenant agrees that except for those chemicals or materials, and their respective quantities, specifically listed on the Environmental Questionnaire (as the same may be updated from time to time as provided below), neither Tenant nor Tenant’s employees, contractors and subcontractors of any tier, entities with a contractual relationship with Tenant (other than Landlord), or any entity acting as an agent or sub-agent of Tenant (collectively, "Tenant's Agents") will produce, use, store or generate any "Hazardous Materials," as that term is defined below, on, under or about the Premises, nor cause any Hazardous Material to be brought upon, placed, stored, manufactured, generated, blended, handled, recycled, used or "Released," as that term is defined below, on, in, under or about the Premises. If any information provided to Landlord by Tenant on the Environmental Questionnaire, or otherwise relating to information concerning Hazardous Materials is intentionally false, incomplete, or misleading in any material respect, the same shall be deemed a default by Tenant under this Lease. Upon Landlord's request, or in the event of any material change in Tenant's use of Hazardous Materials in the Premises, Tenant shall deliver to Landlord an updated Environmental Questionnaire at least once a year. Tenant shall notify Landlord prior to using any Hazardous Materials in the Premises not described on the initial Environmental Questionnaire, and, to the extent such use would, in Landlord's reasonable judgment, cause a material increase in the risk of liability compared to the uses previously allowed in the Premises, such additional use shall be subject to Landlord's prior consent, which may be withheld in Landlord’s reasonable discretion. Tenant shall not install or permit Tenant's Agents to install any underground storage tank on the Premises. For purposes of this Lease, "Hazardous Materials" means all flammable explosives, petroleum and petroleum products, waste oil, radon, radioactive materials, toxic pollutants, asbestos, polychlorinated biphenyls ("PCBs"), medical waste, chemicals known to cause cancer or reproductive toxicity, pollutants, contaminants, hazardous wastes, toxic substances or related materials, including without limitation any chemical, element, compound, mixture, solution, substance, object, waste or any combination thereof, which is or may be hazardous to human health, safety or to the environment due to its radioactivity, ignitability, corrosiveness, reactivity, explosiveness, toxicity, carcinogenicity, infectiousness or other harmful or potentially harmful properties or effects, or defined as, regulated as or included in, the definition of "hazardous substances," "hazardous wastes," "hazardous materials," or "toxic substances" under any Environmental Laws. For purposes of this Lease, "Release" or "Released" or "Releases" shall mean any release, deposit, discharge, emission, leaking, spilling, seeping, migrating, injecting, pumping, pouring, emptying, escaping, dumping, disposing, or other movement of Hazardous Materials into the environment. Landlord acknowledges that Tenant will be installing and using fume hoods in the Premises and that emissions of Hazardous Materials into the air in compliance with all Environmental Laws shall not be considered Releases.

Prohibitions. As a material inducement to Landlord to enter into this Lease with Tenant, Tenant 1">has fully and accurately1">has, to the best of its knowledge, completed Landlord’s Pre-Leasing Environmental Exposure Questionnaire (the 3">"Environmental Questionnaire"3">“Environmental Questionnaire”), which is attached as Exhibit 5">E.5">G. Tenant 7">agrees7">hereby represents, warrants and covenants that except for those chemicals or materials, and their respective quantities, specifically listed on the Environmental 9">Questionnaire (as the same may be updated from time to time as provided below),9">Questionnaire, neither Tenant nor Tenant’s employees, contractors and subcontractors of any tier, entities with a contractual relationship with Tenant (other than Landlord), or any entity acting as an agent or sub-agent of Tenant (collectively, 11">"Tenant'11">“Tenant’s 13">Agents"13">Agents”) will produce, use, store or generate any 15">"Hazardous15">“Hazardous Materials,17">"17">” as that term is defined below, on, under or about the Premises, nor cause19"> or permit any Hazardous Material to be brought upon, placed, stored, manufactured, generated, blended, handled, recycled, used or 21">"Released,"21">“Released,” as that term is defined below, on, in, under or about the Premises. If any information provided to Landlord by Tenant on the Environmental Questionnaire, or otherwise relating to information concerning Hazardous Materials is 23">intentionally23">knowingly false, incomplete, or misleading in any material respect, the same shall be deemed a default by Tenant under this Lease. 25">Upon25">Tenant shall deliver to Landlord an updated Environmental Questionnaire at least once a year, upon Landlord's request, 27">or27">and in the event of any material change in Tenant's use of Hazardous Materials 29">in29">at the 31">Premises, Tenant31">Premises. Landlord’s prior written consent shall 33">deliver33">be required to35"> Landlord an updated Environmental Questionnaire at least once a year. Tenant shall notify Landlord prior to using any Hazardous Materials 37">in37">use for the Premises not described on the initial Environmental Questionnaire, 39">and,39">such consent not to 41">the extent such use would, in Landlord's reasonable judgment, cause a material increase in the risk of liability compared to the uses previously allowed in the Premises, such additional use shall be 43">subject to Landlord's prior consent, which may be withheld in Landlord’s reasonable discretion.43">unreasonably withheld, conditioned, or delayed. Tenant shall not install or permit45"> Tenant's Agents to install any underground storage tank on the Premises. 47">In addition, Tenant agrees that it: # shall not cause or suffer to occur, the Release of any Hazardous Materials at, upon, under or within the Premises or any contiguous or adjacent premises; and # shall not engage in activities at the Premises that result in, give rise to, or lead to the imposition of liability upon Tenant or Landlord or the creation of an environmental lien or use restriction upon the Premises. For purposes of this Lease, 49">"Hazardous Materials"49">“Hazardous Materials” means all flammable explosives, petroleum and petroleum products, waste oil, radon, radioactive materials, toxic pollutants, asbestos, polychlorinated biphenyls 51">("PCBs"51">(“PCBs”), medical waste, chemicals known to cause cancer or reproductive toxicity, pollutants, contaminants, hazardous wastes, toxic substances or related materials, including without limitation any chemical, element, compound, mixture, solution, substance, object, waste or any combination thereof, which is or may be hazardous to human health, safety or to the environment due to its radioactivity, ignitability, corrosiveness, reactivity, explosiveness, toxicity, carcinogenicity, infectiousness or other harmful or potentially harmful properties or effects, or defined as, regulated as or included in, the definition of 53">"hazardous53">“hazardous substances,55">" "hazardous55">” “hazardous wastes,57">" "hazardous57">” “hazardous materials,59">"59">” or 61">"toxic substances"61">“toxic substances” under any Environmental Laws.63"> The term “Hazardous Materials” for purposes of this Lease shall also include any mold, fungus or spores, whether or not the same is defined, listed, or otherwise classified as a “hazardous material” under any Environmental Laws, if such mold, fungus or spores may pose a risk to human health or the environment or negatively impact the value of the Premises. For purposes of this Lease, 65">"Release"65">“Release” or 67">"Released"67">“Released” or 69">"Releases"69">“Releases” shall mean any release, deposit, discharge, emission, leaking, spilling, seeping, migrating, injecting, pumping, pouring, emptying, escaping, dumping, disposing, or other movement of Hazardous Materials into the environment.71"> Landlord acknowledges that Tenant will be installing and using fume hoods in the Premises and that emissions of Hazardous Materials into the air in compliance with all Environmental Laws shall not be considered Releases.

Prohibitions. As a material inducement to Landlord to enter into this Lease with Tenant, Tenant has fully and accurately completed Landlord’s Pre-Leasing Environmental Exposure Questionnaire (the 1">"Environmental Questionnaire"1">“Environmental Questionnaire”), which is attached as 3">Exhibit E.3">[Exhibit 5.3].1.1. Tenant 5">agrees5">hereby represents, warrants and covenants that except for those chemicals or materials, and their respective quantities, specifically listed on the Environmental Questionnaire (as 7">the same may be updated from time to 9">time as provided below)9">time), neither Tenant nor Tenant’s11"> subtenants or assigns, or any of their respective employees, contractors and subcontractors of any tier, entities with a contractual relationship with 13">Tenant13">such parties (other than Landlord), or any entity acting as an agent or sub-agent of 15">Tenant15">such parties or any of the foregoing (collectively, 17">"Tenant's Agents"17">“Tenant Parties”) will produce, use, store or generate any 19">"Hazardous Materials,"19">“Hazardous Materials”, as that term is defined below, on, under or about the Premises, nor cause21"> or permit any Hazardous Material to be brought upon, placed, stored, manufactured, generated, blended, handled, recycled, used or 23">"Released,"23">“Released”, as that term is defined below, on, in, under or about the 25">Premises.25">Premises or Project. If any information provided to Landlord by Tenant on the Environmental Questionnaire, or otherwise relating to information concerning Hazardous Materials is intentionally false, 27">incomplete,27">incomplete or misleading in any material respect, the same shall be deemed a default by Tenant under this Lease. Upon 29">Landlord'29">Landlord’s request, or in the event of any material change in 31">Tenant'31">Tenant’s use of Hazardous Materials 33">in33">at the Premises, Tenant shall deliver to Landlord an updated Environmental 35">Questionnaire at least once a year. Tenant35">Questionnaire. Landlord’s prior written consent shall 37">notify Landlord prior to using37">be required for any Hazardous Materials 39">in39">use for the Premises not described on the initial Environmental Questionnaire, 41">and,41">such consent not to 43">the extent such use would, in Landlord's reasonable judgment, cause a material increase in the risk of liability compared to the uses previously allowed in the Premises, such additional use shall be 45">subject to Landlord's prior consent, which may be withheld in Landlord’s reasonable discretion.45">unreasonably withheld, conditioned or delayed. Tenant shall not install or permit47"> Tenant's Agents to install any underground storage tank on the Premises. 49">In addition, Tenant agrees that it: # shall not cause or suffer to occur, the Release (as defined below) of any Hazardous Materials at, upon, under or within the Premises or any contiguous or adjacent premises; and # shall not engage in activities at the Premises that give rise to, or lead to the imposition of, liability upon Tenant or Landlord or the creation of an environmental lien or use restriction upon the Premises. For purposes of this Lease, 51">"Hazardous Materials"51">“Hazardous Materials” means all flammable explosives, petroleum and petroleum products,53"> waste oil, radon, radioactive materials, toxic pollutants, asbestos, polychlorinated biphenyls 55">("PCBs"55">(“PCBs”), medical waste, chemicals known to cause cancer or reproductive toxicity, pollutants, contaminants, hazardous wastes, toxic substances or related materials, including without limitation any chemical, element, compound, mixture, solution, substance, object, waste or any combination thereof, which is or may57"> hereafter be determined to be hazardous to human health, safety or to the environment due to its radioactivity, ignitability, corrosiveness, reactivity, explosiveness, toxicity, carcinogenicity, infectiousness or other harmful or potentially harmful properties or effects, or defined as, regulated as or included in, the definition of 59">"hazardous substances," "hazardous wastes," "hazardous materials,"59">“hazardous substances”, “hazardous wastes”, “hazardous materials”, or 61">"toxic substances"61">“toxic substances” under any Environmental Laws.63"> The term “Hazardous Materials” for purposes of this Lease shall also include any mold, fungus or spores, whether or not the same is defined, listed, or otherwise classified as a “hazardous material” under any Environmental Laws, if such mold, fungus or spores may pose a risk to human health or the environment. Hazardous Materials shall also include any “biohazardous waste,” “medical waste,” or other waste under California Health and Safety Code Division 20, Chapter 6.1 (Medical Waste Management Act). For purposes of this Lease, 65">"Release"65">“Release” or 67">"Released"67">“Released” or 69">"Releases"69">“Releases” shall mean any release, deposit, discharge, emission, leaking, spilling, seeping, migrating, injecting, pumping, pouring, emptying, escaping, dumping, disposing, or other movement of Hazardous Materials into the environment.71"> Landlord acknowledges that Tenant will be installing and using fume hoods in the Premises and that emissions of Hazardous Materials into the air in compliance with all Environmental Laws shall not be considered Releases.

Prohibitions. As a material inducement to Landlord to enter into this Lease with Tenant, Tenant has fully and accurately completed Landlord’s Pre-Leasing Environmental Exposure Questionnaire (the 1">"Environmental Questionnaire"1">“Environmental Questionnaire”), which is attached as 3">Exhibit E.3">[Exhibit 5.3].1.1. Tenant 5">agrees5">hereby represents, warrants and covenants that except for those chemicals or materials, and their respective quantities, specifically listed on the Environmental 7">Questionnaire (as the same may be updated from time to time as provided below),7">Questionnaire, neither Tenant nor Tenant’s9"> subtenants or assigns, or any of their respective employees, contractors and subcontractors of any tier, entities with a contractual relationship with 11">Tenant11">such parties (other than Landlord), or any entity acting as an agent or sub-agent of 13">Tenant13">such parties or any of the foregoing (collectively, 15">"Tenant's Agents"15">“Tenant Parties”) will produce, use, store or generate any 17">"Hazardous Materials,"17">“Hazardous Materials”, as that term is defined below, on, under or about the Premises, nor cause19"> or permit any Hazardous Material to be brought upon, placed, stored, manufactured, generated, blended, handled, recycled, used or 21">"Released,"21">“Released”, as that term is defined below, on, in, under or about the 23">Premises.23">Premises or Project. If any information provided to Landlord by Tenant on the Environmental Questionnaire, or otherwise relating to information concerning Hazardous Materials is 25">intentionally false, incomplete, or misleading in any material respect, the same shall be deemed a default by Tenant under this Lease. Upon 27">Landlord'27">Landlord’s request, or in the event of any material change in 29">Tenant'29">Tenant’s use of Hazardous Materials 31">in31">at the Premises, Tenant shall deliver to Landlord an updated Environmental 33">Questionnaire at least once a year. Tenant33">Questionnaire. Landlord’s prior written consent shall 35">notify Landlord prior to using35">be required for any Hazardous Materials 37">in37">use for the Premises not described on the initial Environmental Questionnaire, 39">and,39">such consent not to 41">the extent such use would, in Landlord's reasonable judgment, cause a material increase in the risk of liability compared to the uses previously allowed in the Premises, such additional use shall be 43">subject to Landlord's prior consent, which may be withheld in Landlord’s reasonable discretion.43">unreasonably withheld, conditioned or delayed. Tenant shall not install or permit45"> Tenant's Agents to install any underground storage tank on the Premises. 47">In addition, Tenant agrees that it: # shall not cause or suffer to occur, the Release (as defined below) of any Hazardous Materials at, upon, under or within the Premises or any contiguous or adjacent premises; and # shall not engage in activities at the Premises that give rise to, or lead to the imposition of, liability upon Tenant or Landlord or the creation of an environmental lien or use restriction upon the Premises. For purposes of this Lease, 49">"Hazardous Materials"49">“Hazardous Materials” means all flammable explosives, petroleum and petroleum products,51"> waste oil, radon, radioactive materials, toxic pollutants, asbestos, polychlorinated biphenyls 53">("PCBs"53">(“PCBs”), medical waste, chemicals known to cause cancer or reproductive toxicity, pollutants, contaminants, hazardous wastes, toxic substances or related materials, including without limitation any chemical, element, compound, mixture, solution, substance, object, waste or any combination thereof, which is or may55"> hereafter be determined to be hazardous to human health, safety or to the environment due to its radioactivity, ignitability, corrosiveness, reactivity, explosiveness, toxicity, carcinogenicity, infectiousness or other harmful or potentially harmful properties or effects, or defined as, regulated as or included in, the definition of 57">"hazardous substances," "hazardous wastes," "hazardous materials,"57">“hazardous substances”, “hazardous wastes”, “hazardous materials”, or 59">"toxic substances"59">“toxic substances” under any Environmental Laws.61"> The term “Hazardous Materials” for purposes of this Lease shall also include any mold, fungus or spores, whether or not the same is defined, listed, or otherwise classified as a “hazardous material” under any Environmental Laws, if such mold, fungus or spores may pose a risk to human health or the environment or negatively impact the value of the Premises. Hazardous Materials shall also include any “biohazardous waste,” “medical waste,” or other waste under California Health and Safety Code Division 20, Chapter 6.1 (Medical Waste Management Act). For purposes of this Lease, 63">"Release"63">“Release” or 65">"Released"65">“Released” or 67">"Releases"67">“Releases” shall mean any release, deposit, discharge, emission, leaking, spilling, seeping, migrating, injecting, pumping, pouring, emptying, escaping, dumping, disposing, or other movement of Hazardous Materials into the environment.69"> Landlord acknowledges that Tenant will be installing and using fume hoods in the Premises and that emissions of Hazardous Materials into the air in compliance with all Environmental Laws shall not be considered Releases.

Prohibitions. As a material inducement to Landlord to enter into this Lease with Tenant, Tenant has fully and accurately 1">(in all material respects) completed Landlord’s Pre-Leasing Environmental Exposure Questionnaire (the 3">"Environmental Questionnaire"3">“Environmental Questionnaire”), which is attached as Exhibit E. Tenant agrees that except for those chemicals or materials, and their respective quantities, specifically listed on the Environmental Questionnaire (as 5">the same may be updated from time to time as provided 7">below)7">herein), neither Tenant nor Tenant’s employees, contractors and subcontractors of any tier, entities with a contractual relationship with Tenant (other than Landlord), or any entity acting as an agent or sub-agent of Tenant (collectively, "Tenant's Agents") will produce, use, store or generate any "Hazardous Materials," as that term is defined below, 9">except for de minimis quantities of typical cleaning and office supplies, and customary construction materials uses in the course of construction of the Tenant Improvements, all of which shall be stored, used, and disposed of in accordance with Applicable Laws, on, under or about the Premises, nor cause11"> or permit any Hazardous Material to be brought upon, placed, stored, manufactured, generated, blended, handled, recycled, used or "Released," as that term is defined below, on, in, under or about the Premises. If any information provided to Landlord by Tenant on the Environmental Questionnaire, or otherwise relating to information concerning Hazardous Materials is 13">intentionally13">materially false, incomplete, or misleading in any material respect, the same shall be deemed 15">a default15">an Event of Default by 17">Tenant under this Lease. Upon Landlord's request, or in the event of any material change in Tenant's use of Hazardous Materials in the Premises,17">Tenant. Tenant shall deliver to Landlord an updated Environmental Questionnaire at least once a 19">year.19">year, and Tenant shall 21">notify Landlord prior to using any21">update the Environmental Questionnaire when Tenant anticipates a change in the types or amounts of Hazardous Materials 23">Tenant will use in25"> the Premises. Landlord’s prior written consent shall be required to any material change in type or amount of Hazardous Materials use for the Premises not described on the initial Environmental Questionnaire, 27">and,27">such consent not to be unreasonably withheld, conditioned or delayed so long as Tenant’s proposed Hazardous Materials are similar in type and quantity to those used by comparable tenants of First Class Life Science Projects; provided that if the proposed Hazardous Materials are materially similar to the 29">extent such use would,29">Hazardous Materials set forth on the Environmental Questionnaire in 31">Landlord's reasonable judgment, cause a material increase in the risk31">terms of 33">liability compared to the uses previously allowed in the Premises, such additional use shall be subject to33">hazardous character, handling profile, usage and quantity, then Landlord's prior 35">consent, which may35">consent to Tenant’s use of such Hazardous Materials shall not be 37">withheld in Landlord’s reasonable discretion.37">required as long as Tenant provides an updated Environmental Questionnaire to Landlord at least annually. Tenant shall not install or permit39"> Tenant's Agents to install any underground storage tank on the Premises. For purposes of this Lease, "Hazardous Materials" means all flammable explosives, petroleum and petroleum products, waste oil, radon, radioactive materials, toxic pollutants, asbestos, polychlorinated biphenyls 41">("PCBs"41">(“PCBs”), medical waste, chemicals known to cause cancer or reproductive toxicity, pollutants, contaminants, hazardous wastes, toxic substances or related materials, including without limitation any chemical, element, compound, mixture, solution, substance, object, waste or any combination thereof, which is or may be hazardous to human health, safety or to the environment due to its radioactivity, ignitability, corrosiveness, reactivity, explosiveness, toxicity, carcinogenicity, infectiousness or other harmful or potentially harmful properties or effects, or defined as, regulated as or included in, 43">the definition of "hazardous substances," "hazardous wastes," "hazardous materials," or "toxic substances" under any Environmental Laws. For purposes of this Lease, "Release" or "Released" or "Releases" shall mean any release, deposit, discharge, emission, leaking, spilling, seeping, migrating, injecting, pumping, pouring, emptying, escaping, dumping, disposing, or other movement of Hazardous Materials into the environment. Landlord acknowledges that Tenant will be installing and using fume hoods in the Premises and that emissions of Hazardous Materials into the air in compliance with all Environmental Laws shall not be considered Releases.

Prohibitions. As a material inducement to Landlord to enter into this Lease with Tenant, Tenant has fully and 1">accurately1">accurately, to Tenant’s knowledge as of the date of its signature thereon, completed Landlord’s Pre-Leasing Environmental Exposure Questionnaire (the 3">"Environmental Questionnaire"3">“Environmental Questionnaire”), which is attached as Exhibit 5">E.5">E and identifies the “Hazardous Materials,” as that term is defined below, that Tenant reasonably anticipates to be used at the Premises and any related environmental permits that may be required. Tenant agrees that7"> except for those chemicals or materials, and their respective quantities, specifically listed on the Environmental Questionnaire (as the same may be updated from time to time as provided below), neither Tenant nor Tenant’s employees, contractors and subcontractors of any tier, entities with a contractual relationship with Tenant (other than Landlord), or any entity acting as an agent or sub-agent of Tenant (collectively, "Tenant's Agents") will produce, use, store or generate any 9">"Hazardous9">Hazardous Materials,11">" as that term is defined below, on, under or about the 13">Premises,13">Premises in violation of Environmental Laws, nor cause15"> or permit any Hazardous Material to be brought upon, placed, stored, manufactured, generated, blended, handled, recycled, used or "Released," as that term is defined below, on, in, under or about the 17">Premises. If any information provided to Landlord by Tenant on the17">Premises in violation of Environmental 19">Questionnaire, or otherwise relating to information concerning Hazardous Materials is intentionally false, incomplete, or misleading in any material respect, the same shall be deemed a default by Tenant under this Lease.19">Laws. Upon Landlord's 21">request,21">written request (but no more than once each Lease Year), or in the event of any material change in Tenant's use of Hazardous Materials 23">resulting in a new class or category of Hazardous Materials being used in the 25">Premises,25">Premises from that set forth in the Environmental Questionnaire then in place (i.e., changes in non Hazardous Materials or reasonable changes to the amounts or types of Hazardous Materials in the same category are exempt), Tenant shall deliver to Landlord an updated Environmental 27">Questionnaire at least once a year. Tenant27">Questionnaire. Landlord’s prior written consent shall 29">notify Landlord prior29">be required to31"> using any Hazardous Materials 33">in33">use for the Premises35"> that is not described on the 37">initial Environmental Questionnaire,39"> and, to the extent such use 41">would,41">would result in 43">Landlord's reasonable judgment, cause a 45">material increase in the risk45">new class or category of 47">liability compared to the uses previously allowed47">Hazardous Materials being used in the Premises, such additional use shall be subject to Landlord's prior consent, which may be withheld in Landlord’s reasonable discretion.49"> Tenant shall not install or permit Tenant's Agents to install any underground storage tank on the Premises. For purposes of this Lease, "Hazardous Materials" means all flammable explosives, petroleum and petroleum products, waste oil, radon, radioactive materials, toxic pollutants, asbestos, polychlorinated biphenyls 51">("PCBs"51">(“PCBs”), medical waste, chemicals known to cause cancer or reproductive toxicity, pollutants, contaminants, hazardous wastes, toxic substances or related materials, including without limitation any chemical, element, compound, mixture, solution, substance, object, waste or any combination thereof, which is or may be hazardous to human health, safety or to the environment due to its radioactivity, ignitability, corrosiveness, reactivity, explosiveness, toxicity, carcinogenicity, infectiousness or other harmful or potentially harmful properties or effects, or defined as, regulated as or included in, the definition of 53">"hazardous53">“hazardous substances,55">" "hazardous55">” “hazardous wastes,57">" "hazardous57">” “hazardous materials,59">"59">” or 61">"toxic substances"61">“toxic substances” under any Environmental Laws. 63">For63">The term “Hazardous Materials” for purposes of this 65">Lease, "Release"65">Lease shall also include any mold, fungus or 67">"Released"67">spores, whether or 69">"Releases" shall mean69">not the same is defined, listed, or otherwise classified as a “hazardous material” under any 71">release, deposit, discharge, emission, leaking, spilling, seeping, migrating, injecting, pumping, pouring, emptying, escaping, dumping, disposing,71">Environmental Laws, if such mold, fungus or 73">other movement73">spores may pose a risk to human health or the environment or negatively impact the value of 75">Hazardous Materials into the77"> environment. Landlord acknowledges that Tenant will be installing and using fume hoods in the Premises and that emissions of Hazardous Materials into the air in compliance with all Environmental Laws shall not be considered Releases.

Prohibitions. 1">As a material inducement1">Prior to 3">occupying the Premises, Tenant shall provide Landlord 5">to enter into this Lease with 7">Tenant, Tenant has fully and accurately completed Landlord’s Pre-Leasing Environmental Exposure Questionnaire7">the environmental questionnaire (the "Environmental Questionnaire"), 9">which is9">in the form attached as Exhibit 11">E.11">G. Prior to the date of this Lease, Tenant 13">agrees13">provided a completed version of the Environmental Questionnaire to Landlord, which Environmental Questionnaire shall be executed by Tenant (and updated as necessary) prior to occupying the Premises. Tenant hereby represents, warrants and covenants that except for those chemicals or materials, and their respective quantities,15"> specifically listed on the Environmental Questionnaire (as the same may be updated from time to time as provided below)17">,17"> or any similar chemicals or materials used for substantially the same purposes in substitution thereof in compliance with Environmental Laws, neither Tenant nor 19">Tenant’19">Tenant's employees, contractors and subcontractors of any tier, entities with a contractual relationship with Tenant (other than Landlord), or any entity acting as an agent or sub-agent of Tenant (collectively, "Tenant's Agents") will produce, use, store or generate any 21">"Hazardous21">Hazardous Materials,23">" as that term is defined below, on, under or about the Premises, nor cause25"> or permit any Hazardous Material to be brought upon, placed, stored, manufactured, generated, blended, handled, recycled, used or "Released," as that term is defined below, on, in, under or about the Premises. If any information provided to Landlord by Tenant on the Environmental Questionnaire, or otherwise relating to information concerning Hazardous Materials is 27">intentionally false, incomplete, or misleading in any material respect, the same shall be deemed a default by Tenant under this Lease. Upon Landlord's 29">request,29">request (but no more than once every twelve (12) months), or in the event of any material change in Tenant's use of Hazardous Materials in the Premises, Tenant shall deliver to Landlord an updated Environmental 31">Questionnaire at least once a year.31">Questionnaire. Tenant shall notify Landlord prior to using any Hazardous Materials in the 33">Premises33">Project not described on the initial Environmental Questionnaire, 35">and, to the extent35">and such37"> use would, in Landlord's reasonable judgment, cause a material increase in the risk of liability compared to the uses previously allowed in the Premises, such additional use shall be subject to 39">Landlord's prior consent, which may be withheld in Landlord’s reasonable discretion.39">all of the provisions of this Lease. Tenant shall not install or permit 41">Tenant's Agents to install any underground storage tank on the Premises.43"> In addition, Tenant agrees that shall not cause or suffer to occur, the Release of any Hazardous Materials at, upon, under or within the Premises or any contiguous or adjacent premises. For purposes of this Lease, "Hazardous Materials" means all flammable explosives, petroleum and petroleum products, waste oil, radon, radioactive materials, toxic pollutants, asbestos, polychlorinated biphenyls ("PCBs"), medical waste, chemicals known to cause cancer or reproductive toxicity, pollutants, contaminants, hazardous wastes, toxic substances or related materials, including without limitation any chemical, element, compound, mixture, solution, substance, object, waste or any combination thereof, which is or may be hazardous to human health, safety or to the environment due to its radioactivity, ignitability, corrosiveness, reactivity, explosiveness, toxicity, carcinogenicity, infectiousness or other harmful or potentially harmful properties or effects, or defined as, regulated as or included in, the definition of "hazardous substances," "hazardous wastes," "hazardous materials," or "toxic substances" under any Environmental Laws. 45">The term "Hazardous Materials" for purposes of this Lease shall also include any mold, fungus or spores, whether or not the same is defined, listed, or otherwise classified as a "hazardous material" under any Environmental Laws, if such mold, fungus or spores may pose a risk to human health or the environment or negatively impact the value of the Premises. For purposes of this Lease, "Release" or "Released" or "Releases" shall mean any release, deposit, discharge, emission, leaking, spilling, seeping, migrating, injecting, pumping, pouring, emptying, escaping, dumping, disposing, or other movement of Hazardous Materials into the environment.47"> Landlord acknowledges that Tenant will be installing and using fume hoods in the Premises and that emissions of Hazardous Materials into the air in compliance with all Environmental Laws shall not be considered Releases.

0">Prohibitions. As a material inducement to Landlord to enter into this Lease with Tenant, Tenant has fully and accurately completed Landlord’s Pre-Leasing Environmental Exposure Questionnaire (the "Environmental Questionnaire"), which is attached as Exhibit E. Tenant agrees that except for those chemicals or materials, and their respective quantities, specifically listed on the Environmental Questionnaire (as the same may be updated from time to time as provided below), neither Tenant nor Tenant’s employees, contractors and subcontractors of any tier, entities with a contractual relationship with Tenant (other than Landlord), or any entity acting as an agent or sub-agent of Tenant (collectively, "Tenant's Agents") will produce, use, store or generate any "Hazardous Materials," as that term is defined below, on, under or about the Premises, nor cause any Hazardous Material to be brought upon, placed, stored, manufactured, generated, blended, handled, recycled, used or "Released," as that term is defined below, on, in, under or about the Premises. If any information provided to Landlord by Tenant on the Environmental Questionnaire, or otherwise relating to information concerning Hazardous Materials is intentionally false, incomplete, or misleading in any material respect, the same shall be deemed a default by Tenant under this Lease. Upon Landlord's request, or in the event of any material change in Tenant's use of Hazardous Materials in the Premises, Tenant shall deliver to Landlord an updated Environmental Questionnaire at least once a year. Tenant shall notify Landlord prior to using any Hazardous Materials in the Premises not described on the initial Environmental Questionnaire, and, to the extent such use would, in Landlord's reasonable judgment, cause a material increase in the risk of liability compared to the uses previously allowed in the Premises, such additional use shall be subject to Landlord's prior consent, which may be withheld in Landlord’s reasonable discretion. Tenant shall not install or permit Tenant's Agents to install any underground storage tank on the Premises. For purposes of this Lease, "Hazardous Materials" means all flammable explosives, petroleum and petroleum products, waste oil, radon, radioactive materials, toxic pollutants, asbestos, polychlorinated biphenyls 2">("PCBs"2">(“PCBs”), medical waste, chemicals known to cause cancer or reproductive toxicity, pollutants, contaminants, hazardous wastes, toxic substances or related materials, including without limitation any chemical, element, compound, mixture, solution, substance, object, waste or any combination thereof, which is or may be hazardous to human health, safety or to the environment due to its radioactivity, ignitability, corrosiveness, reactivity, explosiveness, toxicity, carcinogenicity, infectiousness or other harmful or potentially harmful properties or effects, or defined as, regulated as or included in, the definition of 4">"hazardous4">“hazardous substances,6">" "hazardous6">” “hazardous wastes,8">" "hazardous8">” “hazardous materials,10">"10">” or 12">"toxic substances"12">“toxic substances” under any Environmental Laws. For purposes of this Lease, "Release" or "Released" or "Releases" shall mean any release, deposit, discharge, emission, leaking, spilling, seeping, migrating, injecting, pumping, pouring, emptying, escaping, dumping, disposing, or other movement of Hazardous Materials into the environment. Landlord acknowledges that Tenant 14">will14">may be installing and using fume hoods in the Premises and that emissions of Hazardous Materials into the air in compliance with all Environmental Laws shall not be considered Releases.