Final Working Drawings. After the Preliminary Plans have been approved by Landlord, Tenant shall cause Tenant’s Architect and the Engineers to prepare and submit for Landlord’s approval complete and detailed construction plans and specifications, including a fully coordinated set of architectural, structural, mechanical, fire protection, electrical and plumbing working drawings for the Tenant Improvement Work, in a form that is sufficiently complete to permit subcontractors to bid on the work, obtain all required Permits (as defined in [Section 3.4], below) and commence construction (the “Final Working Drawings”). The Tenant Improvements shall be designed in accordance with the LEED Design/Operational Requirements and the Final Working Drawings shall incorporate the LEED Design/Operational Requirements. Tenant shall furnish Landlord with two (2) hard copies signed by Tenant and one (1) electronic version of such Final Working Drawings. Landlord shall approve or disapprove the Final Working Drawings by giving written notice to Tenant within fifteen (15) Business Days after receipt thereof. Landlord shall not unreasonably withhold its approval of the Final Working Drawings, provided that, without limiting the generality of the foregoing, Landlord shall be entitled to withhold its consent to the Final Working Drawings for any of the reasons specified in [Section 2.2.1] above, or if in Landlord’s good faith judgment, the Final Working Drawings are inconsistent with, or do not conform to, the Approved Preliminary Plans. If Landlord disapproves the Final Working Drawings, Landlord shall return the Final Working Drawings to Tenant with a statement of Landlord’s reasons for disapproval and/or specifying any required corrections or revisions. Landlord shall approve or disapprove of any such revisions to the Final Working Drawings within seven (7) Business Days after receipt of such revisions. This procedure shall be repeated until Landlord approves the Final Working Drawings (as so approved, the “Approved TI Construction Drawings”). Tenant shall include provisions in it Design Professional Agreements (as defined in [Section 2.2.4]) which expressly allow Landlord to use any and all of the Approved TI Construction Drawings for the Tenant Improvements without any additional cost or payment if the Lease is terminated, subject to Landlord agreeing to indemnify Tenant’s Architect and Engineers in question if Landlord elects to use any of the Approved TI Construction Drawings without retaining Tenant’s Architect or Engineer for the portion of Tenant’s Work covered by the Design Profession Agreement in question.

Upon the approval by Tenant and Landlord of the Final Working Drawings. After the Preliminary Plans have been approved by Landlord,Space Plan, Tenant shall cause Tenant’s Architect and the Engineers to prepare the working plans and submitspecifications for the improvements Tenant desires to be constructed in the Premises or portion thereof. The working plans and specifications shall show improvements that conform to the Final Space Plan (subject to any deviation from the Final Space Plan that is mutually agreed to by Landlord and Tenant), comply with applicable building codes and other Legal Requirements and shall be in sufficient detail as to enable the selected contractor to obtain all necessary governmental permits for commencement of the improvements and to secure complete bids from qualified contractors to perform the work. Tenant shall deliver the completed working plans and specifications to Landlord for Landlord’s review and Landlord shall provide its reasonable approval completeor disapproval thereof within five (5) business days after its receipt thereof. Tenant shall cause Tenant’s Architect to revise the working plans and detailed constructionspecifications to address any reasonable objections raised by Landlord and shall resubmit the revised working plans and specifications to Landlord within five (5) business days after receipt of Landlord’s objections. This procedure shall be followed until all objections have been resolved and the working plans and specifications approved. In no event shall such approval of the working plans and specifications by Landlord be deemed to constitute a representation by Landlord that the work called for in the working plans and specifications complies with applicable Legal Requirements nor shall such consent release Tenant from Tenant’s obligation to supply working plans and specifications which conform to applicable Legal Requirements. (The working plans and specifications, including a fully coordinated set of architectural, structural, mechanical, fire protection, electricalas approved in writing by Tenant and plumbing working drawings forLandlord, are hereinafter called the Tenant Improvement Work, in a form that is sufficiently complete“Final Plans” and the improvements to permit subcontractors to bid on the work, obtain all required Permits (as defined in [Section 3.4], below) and commence construction (the “Final Working Drawings”). The Tenant Improvements shall be designedperformed in accordance with the LEED Design/Operational Requirements andFinal Plans are hereinafter called the Final Working Drawings shall incorporate“Tenant Improvements”). In the LEED Design/Operational Requirements.event Tenant shall furnish Landlord with two (2) hard copies signed by Tenant and one (1) electronic version of such Final Working Drawings. Landlord shall approve or disapprove the Final Working Drawings by giving written noticeelects to Tenant within fifteen (15) Business Days after receipt thereof. Landlord shall not unreasonably withhold its approvalimprove portions of the Final Working Drawings, provided that, without limiting the generality of the foregoing, Landlord shall be entitledPremises at different times and elects to withhold its consentprepare separate space plans and final plans for each project (as opposed to the Final Working Drawings for any of the reasons specified in [Section 2.2.1] above, or if in Landlord’s good faith judgment, the Final Working Drawings are inconsistent with, or do not conform to, the Approved Preliminary Plans. If Landlord disapproves the Final Working Drawings, Landlord shall return the Final Working Drawings to Tenant withpreparing a statement of Landlord’s reasons for disapproval and/or specifying any required corrections or revisions. Landlord shall approve or disapprove of any such revisions to the Final Working Drawings within seven (7) Business Days after receipt of such revisions. This procedure shall be repeated until Landlord approves the Final Working Drawings (as so approved, the “Approved TI Construction Drawings”). Tenant shall include provisions in it Design Professional Agreements (as defined in [Section 2.2.4]) which expressly allow Landlord to use anycomprehensive space plan and final plans depicting all of the Approved TI Construction Drawingsimprovements Tenant desires and then phasing construction thereof), then Tenant shall prepare a space plan and final plans for each project in accordance with the Tenant Improvements without any additional cost or payment if the Lease is terminated, subject to Landlord agreeing to indemnify Tenant’s Architect and Engineers in question if Landlord elects to use anyprovisions of the Approved TI Construction Drawings without retaining Tenant’s Architect or Engineer for the portion of Tenant’s Work covered by the Design Profession Agreement in question.this Paragraph 5.a.

Final Working Drawings. After the Preliminary Plans have been approved by Landlord, Tenant shall cause Tenant’s Architect and the Engineers to prepare and submit for Landlord’s approval complete and detailed construction plans and specifications, including a fully coordinated set of architectural, structural, mechanical, fire protection, electrical and plumbing working drawings for the Tenant Improvement Work,If Landlord determines at any time that changes in a form that is sufficiently complete to permit subcontractors to bid on the work, obtain all required Permits (as defined in [Section 3.4], below) and commence construction (the “Final Working Drawings”). The Tenant Improvements shall be designed in accordance with the LEED Design/Operational Requirements and the Final TI Working Drawings shall incorporate the LEED Design/Operational Requirements. Tenant shall furnish Landlord with two (2) hard copies signed by Tenant and one (1) electronic version of such Final Working Drawings. Landlord shall approve or disapprove the Final Working Drawings by giving written notice to Tenant within fifteen (15) Business Days after receipt thereof. Landlord shall not unreasonably withhold its approval of the Final Working Drawings, provided that, without limiting the generality of the foregoing, Landlord shall be entitled to withhold its consent to the Final Working Drawings forin any of the reasons specified in [Section 2.2.1] above, or if in Landlord’s good faith judgment, the Final Working Drawings are inconsistent with, or do not conform to, the Approved Preliminary Plans. If Landlord disapproves the Final Working Drawings, Landlord shall return the Final Working Drawings to Tenant with a statement of Landlord’s reasons for disapproval and/or specifying any required corrections or revisions. Landlord shall approve or disapprove of any such revisions to the Final Working Drawings within seven (7) Business Days after receipt of such revisions. This procedure shall be repeated until Landlord approves the Final Working Drawings (as so approved, the “Approved TI Construction Drawings”). Tenant shall include provisions in it Design Professional Agreements (as defined in [Section 2.2.4]) which expressly allow Landlord to use any and allother aspect of the Approved TI Construction Drawings forPlans relating to any item of Landlord's TI Work are required as a result of applicable law or governmental requirements, or are required as a result of unanticipated conditions encountered in the course of construction, then Landlord shall promptly # advise Tenant of such circumstances and # at Tenant's sole cost and expense, subject to Landlord's payment of the Tenant Improvements without any additional cost or payment ifImprovement Allowance and, to the Lease is terminated, subjectextent requested by Tenant, the Additional TI Allowance, cause revised Final TI Working Drawings to be prepared by the Architect and submitted to Tenant, for Tenant's approval, which shall not be unreasonably withheld. Failure of Tenant to deliver to Landlord agreeingwritten notice of disapproval and specification of such required changes on or before any deadline reasonably specified by Landlord (which shall not be less than three (3) business days after delivery thereof to indemnify Tenant’Tenant) shall constitute and be deemed to be a Tenant Delay to the extent Landlord is delayed in completing Landlord’s Architect and Engineers in question if Landlord elects to use any of the Approved TI Construction Drawings without retaining Tenant’s Architect or Engineer for the portion of Tenant’s Work covered by the Design Profession Agreement in question.Work.

FinalApproved Plans and Working Drawings. After the Preliminary Plans have been approved by Landlord,Drawings for Tenant Improvements. Tenant shall promptly and diligently work with the Architect to cause Tenant’s Architectto be prepared and delivered to Landlord for approval (which approval shall not be unreasonably withheld, conditioned or delayed by Landlord) proposed schematic plans and outline specifications for the Tenant Improvements, which shall include two (2) separate designs for the 1st floor of the Premises, one of which shall be for a standard office/laboratory design, similar to that on the 2nd and 3rd floors of the Premises (the “Standard Buildout”), and the Engineers to prepare and submitother of which shall be for Landlord’s approval complete and detailed constructiona “GMP manufacturing suite” (the “GMP Suite”). Landlord shall reimburse the Architect directly for the cost of the initial test-fit plans and specifications,outline specifications and one revision thereof, and such costs shall not be charged to the Tenant Improvement Allowance. Following mutual approval of such proposed schematic plans and outline specifications by Landlord and by Tenant (as so approved, the “Approved Schematic Plans”), Tenant shall then work with the Architect to cause to be prepared, promptly and diligently (assuming timely delivery by Landlord of any information and decisions required to be furnished or made by Landlord in order to permit preparation of final working drawings, all of which information and decisions Landlord will deliver promptly and with reasonable diligence), and delivered to Landlord for approval (which approval shall not be unreasonably withheld, conditioned or delayed by Landlord) final detailed working drawings and specifications for the Tenant Improvements, including a fully coordinated set of architectural, structural,(without limitation) any applicable life safety, mechanical, fire protection, electrical and plumbing working drawings for the Tenant Improvement Work, in a form that is sufficiently complete to permit subcontractors to bid on the work, obtain all required Permits (as defined in [Section 3.4]and final architectural drawings (collectively, “Final TI Working Drawings”), below) and commence construction (the “Final Working Drawings”). The Tenant Improvements shall be designed in accordance with the LEED Design/Operational Requirements and thewhich Final TI Working Drawings shall incorporatesubstantially conform to the LEED Design/Operational Requirements.Approved Schematic Plans. Upon receipt from Tenant of proposed schematic plans and outline specifications, proposed Final TI Working Drawings, any other plans and specifications, or any revisions or resubmittals of any of the foregoing, as applicable, Landlord shall furnish Landlordpromptly and diligently (and in all events within 10 business days after receipt in the case of an initial submittal of schematic plans and outline specifications or proposed Final TI Working Drawings, and within 5 business days after receipt in the case of any other plans and specifications or any revisions or resubmittals of any of the foregoing) either approve such proposed schematic plans and outline specifications or proposed Final TI Working Drawings, as applicable, or set forth in writing with two (2) hard copies signed by Tenant and one (1) electronic versionparticularity any changes necessary to bring the aspects of such proposed schematic plans and outline specifications or proposed Final Working Drawings. Landlord shall approve or disapprove the FinalTI Working Drawings by giving written noticeinto a form which will be reasonably acceptable to Tenant within fifteen (15) Business Days after receipt thereof. Landlord shall not unreasonably withhold itsLandlord. Upon approval of the Final TI Working Drawings, provided that, without limitingDrawings by Landlord and Tenant, the generalityFinal TI Working Drawings shall constitute the “Approved TI Plans,” superseding (to the extent of any inconsistencies) any inconsistent features of the foregoing,previously existing Approved Schematic Plans. Tenant shall respond to any request for information or approval of plans or drawings from Landlord shall be entitledor Architect within five (5) business days. Tenant acknowledges that the Tenant Improvements (not including improvements in the GMP Suite) will include the items set forth on [Schedule 2] to withhold its consentthis [Exhibit B], in order to allow the Final Working Drawings for anyPremises to achieve a LEED "Silver" certification level. For the avoidance of doubt, the reasons specified in [Section 2.2.1] above, or if in Landlord’s good faith judgment, the Final Working Drawings are inconsistent with, orTenant Improvements do not conform to, the Approved Preliminary Plans. If Landlord disapproves the Final Working Drawings, Landlord shall return the Final Working Drawingsneed to Tenant with a statement of Landlord’s reasons for disapproval and/or specifying any required corrections or revisions. Landlord shall approve or disapprove of any such revisions to the Final Working Drawings within seven (7) Business Days after receipt of such revisions. This procedure shall be repeated until Landlord approves the Final Working Drawings (as so approved, the “Approved TI Construction Drawings”). Tenant shall include provisions in it Design Professional Agreements (as defined in [Section 2.2.4]) which expressly allow Landlord to use any and all of the Approved TI Construction Drawings forPremises and Tenant may choose not to perform improvements in, or perform only minimal improvements in, a floor of the Premises, provided that Tenant Improvements without any additional costhereby agrees that Tenant shall perform improvements or payment ifAlterations to build out the entirety of the Premises to a commercially reasonable level beyond the Warm Shell Condition prior to the expiration of the third (3rd) full year of the Lease is terminated,Term, subject to Landlord agreeing to indemnify Tenant’s Architect and Engineers in question if Landlord elects to use any of the Approved TI Construction Drawings without retaining Tenant’s Architect or Engineer for the portion of Tenant’s Work covered by the Design Profession Agreement in question.Force Majeure.

Final Working Drawings. AfterNo Liability. Landlord has previously provided to Tenant a set of the Building Plans. Tenant’s Architect shall be responsible for performing all necessary field measurements and confirming the completeness and accuracy of such drawings. Landlord’s sole interest in reviewing and approving the Space Plan, the Preliminary Plans have been approvedand Final Working Drawings is to protect the Building and Landlord’s interests, and no such review or approval by Landlord shall be deemed to # create any liability of any kind on the part of Landlord, including, but not limited to, liability for design, engineering or fitness for a particular purpose, or # constitute a representation on the part of Landlord or any person consulted by Landlord in connection with such review and approval that the Space Plan, the Preliminary Plans or Final Working Drawings are correct or accurate, or are in compliance with any Applicable Laws or the requirements of this Agreement. Without limiting the foregoing, Tenant shall causebe responsible for ensuring # that all elements of the design of the Final Working Drawings comply with Applicable Laws and are otherwise suitable for Tenant’s Architectuse of the Premises, and # that no Tenant Improvement impairs any Base Building Systems or Landlord’s ability to perform its obligations under this Agreement or the Engineers to prepareLease, and submit for Landlord’s approval complete and detailed construction plans and specifications, including a fully coordinated set of architectural, structural, mechanical, fire protection, electrical and plumbing working drawings for the Tenant Improvement Work, in a form that is sufficiently complete to permit subcontractors to bid on the work, obtain all required Permits (as defined in [Section 3.4], below) and commence construction (the “Final Working Drawings”). The Tenant Improvements shall be designed in accordance with the LEED Design/Operational Requirements and the Final Working Drawings shall incorporate the LEED Design/Operational Requirements.not relieve Tenant shall furnishfrom such responsibility. Further, if Landlord with two (2) hard copies signed by Tenant and one (1) electronic versionincurs any cost as a result of such Final Working Drawings. Landlord shall approve or disapprove the Final Working Drawings by giving written notice to Tenant within fifteen (15) Business Days after receipt thereof. Landlord shall not unreasonably withhold its approvalany failure of the Final Working Drawings, provided that, without limiting the generality of the foregoing, Landlord shall be entitled to withhold its consent to the Final Working Drawings for any of the reasons specified in [Section 2.2.1] above, or if in Landlord’s good faith judgment, the Final Working Drawings are inconsistent with, or do not conform to, the Approved Preliminary Plans. If Landlord disapproves the Final Working Drawings, Landlord shall return the Final Working Drawings to Tenantcomply with Applicable Laws or as a statementresult of any impairment of any Base Building Systems or of Landlord’s reasons for disapproval and/ability to perform its obligations under this Agreement or specifyingthe Lease resulting from any required corrections or revisions. Landlord shall approve or disapprove of any such revisions todefect in the Final Working Drawings within seven (7) Business Days after receipt of such revisions. This procedure shall be repeated untilDrawings, then Tenant, upon written notice and request from Landlord, shall, at Landlord’s option, either # assign to Landlord approvesany right Tenant may have under the Final Working Drawings (as so approved, the “Approved TI Construction Drawings”). Tenant shall include provisions in it Design Professional Agreements (as defined in [Section 2.2.4])(defined below) to recover such cost from Tenant’s Architect and/or Engineers, as the case may be, or # at Tenant’s expense, use reasonable efforts to enforce such right directly against Tenant’s Architect and/or Engineers, as the case may be, for Landlord’s benefit. As used herein, “Design Professional Agreements” means the agreements between Tenant and Tenant’s Architect and Engineers pursuant to which expressly allow Landlord to use any and all of the Approved TI Construction Drawings for the Tenant Improvements without any additional costhave been or payment if the Lease is terminated, subject to Landlord agreeing to indemnify Tenant’s Architect and Engineers in question if Landlord elects to use any of the Approved TI Construction Drawings without retaining Tenant’s Architect or Engineer for the portion of Tenant’s Work covered by the Design Profession Agreement in question.will be prepared.