Exercise of Option and Purchase of Shares. Each employee who continues to be a Participant in the Plan on the Exercise Date shall be deemed to have exercised his or her Option on such date and shall acquire from the Company such number of whole shares of Common Stock reserved for the purpose of the Plan as his or her accumulated payroll deductions on such date will purchase at the Option Price, subject to any other limitations contained in the Plan. Any amount remaining in a Participant’s account at the end of an Offering solely by reason of the inability to purchase a fractional share will be carried forward to the next Offering; any other balance remaining in a Participant’s account at the end of an Offering will be refunded to the Participant promptly.

Purchase Option. Provided that: (a) (i) no Event of Default shall have occurred and be continuing, and # Lessee has not defaulted in its rights pursuant to [Section 1 or 2] of this Exhibit C, then commencing on the first day of the tenth (10th) anniversary of the Effective Date and ending three (3) months thereafter, or (b) (i) Lessee has exercised the applicable Extension Option pursuant to the terms and provisions of this Lease, # no Event of Default shall have occurred and be continuing, and # Lessee has not defaulted in its rights pursuant to: # the purchase option in [clause (a) of this Section 3], or # [Section 1 or 2] of this Exhibit C, then during the period commencing on the first day of each extension term and ending three (3) months thereafter (each of [(a) or (b)], an “Option Period”), Lessee shall have the option to purchase Lessor’s Interest from Lessor at a price equal to the greater of: # fair market value (as determined by an appraisal conducted by an MAI designated appraiser mutually chosen by Lessor and Lessee, which appraisal shall assume the highest and best use of the Property and not just the Permitted Use) and # for the three (3) month period following the tenth (10th) anniversary of the Effective Date, one hundred twenty percent (120%), # during the first Extension Option one hundred thirty-five percent (135%), during the second Extension Option one hundred forty percent (140%), during the third Extension Option one hundred fifty percent (150%), and during the fourth Extension Option one hundred sixty percent (160%) of Lessor’s total investment in the Property (i.e., the sum of: # the original purchase price paid by the then lessor under this Lease, # any subsequent fundings advanced by Lessor to Lessee related to the Property, and # Lessee’s closing costs (the “Project Purchase Price”). Lessee shall exercise its rights hereunder by giving written notice to Lessor prior to the expiration of the Option Period (“Option Exercise Notice”). If Lessee delivers to Lessor an Option Exercise Notice, then Lessor and Lessee shall negotiate in good faith to enter into a purchase and sale agreement pursuant to which Lessor and Lessee shall consummate the purchase and sale of the Property on the date that is ninety (90) days after receipt by Lessor of the Option Exercise Notice for the Project Purchase Price, free and clear of all liens, pledges, security interests and other encumbrances (other than the Permitted Exceptions), and otherwise on the customary terms and conditions as are reasonably acceptable to Lessor and Lessee. Lessee shall be responsible for paying all costs in connection with the purchase and transfer of the Property, including, but not limited to, transfer costs and taxes, expenses of Lessor’s attorney fees, and any prepayment costs, penalties, or premiums, including, without limitation, all costs with respect to any defeasance (including the purchase of any securities) of any loan on the property, Lessor incurs to prepay any loan on the property in excess of the outstanding principal balance of the Lessor’s loan, if any. In the event that Lessee defaults in its obligation to close on the acquisition of the Property pursuant to this [Section 3] of this Exhibit C from Lessor if and when required to do so under this [Section 3] of this Exhibit C, Lessor, in addition to any other rights or remedies available at law or in equity, shall have the right to recover Lessor’s reasonable legal fees and other out of pocket expenses actually incurred in connection therewith. Additionally, if Lessee defaults in its obligation to purchase Lessor’s Interest if and when required to do so under this [Section 3] of this Exhibit C, then Lessee shall have no further rights and Lessor shall have no further obligations under this [Section 3] of this Exhibit C. Notwithstanding anything to the contrary, Lessee’s rights hereunder as to the Lessor’s Interest shall terminate and be null and void and of no further force and effect if this Lease terminates or upon Lessee’s purchase of Lessor’s Interest. In any such event, Lessee shall execute a quitclaim deed and/or such other documents as Lessor shall reasonably request evidencing the termination of Lessee’s right hereunder.

Exercise of Option. The Purchaser hereby elects to exercise the Option to purchase shares of Common Stock (“Shares”), all of which are vested pursuant to the terms of the Stock Option Agreement. The total Exercise Price for all of the Shares is (Total Shares times Exercise Price per Share).

Exercise of Option. I hereby elect to exercise the Option to purchase the following number of Shares, all of with are Vested Shares in accordance with the Notice and/or Option Agreement:

Exercise of Option. Effective as of today, the undersigned (“Employee”) hereby elects to exercise Employee’s option to purchase shares of the Common Stock (the “Shares”) of Protagonist Therapeutics, Inc. (the “Company”) under and pursuant to [[Organization A:Organization]]’s 2007 Stock Option and Incentive Plan (the “Plan”) and the Stock Option Agreement dated , (the “Option Agreement”). The purchase price for the Shares shall be $ as required by the Option Agreement. Employee herewith delivers to [[Organization A:Organization]] the full Exercise Price for the Shares.

The Company may exercise the Purchase Option by delivering or mailing to the Participant (or the Participant’s estate), within 180 days after the termination of the Service of the Participant, a written notice of exercise of the Purchase Option. Such notice shall specify the number of Shares to be purchased. If and to the extent the Purchase Option is not so exercised by the giving of such a notice within such 180-day period, the Purchase Option shall automatically expire and terminate effective upon the expiration of such180-day period.

Exercise of Option. Effective as of today, the undersigned (“Optionee”) hereby elects to exercise Optionee’s option to purchase ​ shares of the Common Stock (the “Shares”) of Assembly Biosciences, Inc. (the “Company”) under and pursuant to the Company’s 2019 Inducement Award Plan (as amended from time to time, the “Plan”) and the Notice of Stock Option Grant dated ​, 20​ with its attached Stock Option Agreement (the “Option Agreement”). The purchase price for the Shares shall be ​ as required by this Option Agreement. Optionee herewith delivers to the Company the full Exercise Price for the Shares.

Exercise of Option. The times, circumstances and conditions under which an Option shall be exercisable shall be determined by the Committee in its sole discretion and set forth in the Award Agreement. Unless otherwise determined by the Committee and set forth in the Award Agreement, each Option granted to an Employee for an eight-year term shall vest and become exercisable as to ten (10%) percent of the Shares covered thereby on the third anniversary of Continuous Service after the Grant Date, as to twenty (20%) percent of the Shares covered thereby on the fourth anniversary of Continuous Service after the Grant Date, as to twenty (20%) percent of the Shares covered thereby on the fifth anniversary of Continuous Service after the Grant Date, as to twenty-five (25%) percent of the Shares covered thereby on the sixth anniversary of Continuous Service after the Grant Date, as to fifteen (15%) percent of the Shares covered thereby on the seventh anniversary of Continuous Service after the Grant Date, and as to ten (10%) percent of the Shares covered thereby on the eighth anniversary of Continuous Service after the Grant Date. Each Option granted for a five-year term shall vest and become exercisable at such time or times as shall be determined by the Committee and set forth in the Award Agreement. The Committee shall have the discretion to determine whether and to what extent the vesting of Options shall be tolled during any unpaid leave of absence; provided, however, that in the absence of such determination, vesting of Options shall be tolled during any such leave approved by the Company.

Exercise of Option. Landlord will give notice to Tenant (an “Offering Notice”) setting forth Landlord’s intent to construct the Station 5 Building and to make the Station 5 Building available for lease. The Offering Notice shall include # the rentable square footage of the Station 5 Building that Landlord intends to construct, for which rentable square footage Landlord shall have obtained approvals through the Site Plan and Architectural Review process of the City of San Mateo, # the six-month time period during which Landlord anticipates completing the base building improvements of the Station 5 Building and delivering possession thereof for completion of tenant improvements, and # a copy of the building plans for the Station 5 Building. Tenant shall exercise the Expansion Option, if at all, by giving Landlord unconditional, irrevocable written notice of such election (the “Expansion Exercise Notice”) no later than thirty (30) days after the date of the Offering Notice, the time of such exercise being of the essence. Tenant’s Expansion Exercise Notice shall set forth the rentable square footage of the Station 5

Exercise of Option. This Option is exercisable as follows: