[Section 1.1] of the Agreement is hereby amended to add the following new defined terms:

[Section 1.01] of the Loan and Servicing Agreement is hereby amended by adding the following definition in proper alphabetical sequence:

[Section 1.1] of the Existing Credit Agreement is hereby amended by adding the following defined terms in appropriate alphabetical order:

[Schedule 1.01(b)] to the Credit Agreement is hereby amended and restated to read in its entirety as set forth on Annex I hereto.

[Section 1.01] (Defined Terms) of the Credit Agreement is hereby amended by replacing the defined terms “Eurodollar Rate”, “Maturity Date”, and “Replacement Rate” in their entirety with the following corresponding terms:

[Section 1.01] of the Credit Agreement is hereby amended by deleting the definitions of “Fee Letter” and “Loan Documents” in their entirety and inserting the following definitions in their stead:

[Schedule 1.9] sets forth a complete and accurate list of all [[AstraZeneca:Organization]] Patents in existence as of the Effective Date, indicating the owner or co-owners thereof (including Affiliates of [[AstraZeneca:Organization]]), if such [[AstraZeneca:Organization]] Patent is not solely owned by [[AstraZeneca:Organization]];

[Section 1.02] (Other Interpretive Provisions) of the Credit Agreement is amended by adding a new clause (d) thereto as follows:

[Schedule 1.1] to the Loan Agreement is hereby amended and restated in its entirety as attached to this Amendment.

[Section 1.1] of the Receivables Purchase Agreement is hereby amended by amending and restating the definitions of “Adjusted Discount Rate”, “Business Day”, “Discount Rate” and “Scheduled Termination Date” in their entirety as follows: