Duties and Location. Executive shall perform such duties as are customarily associated with the position of Senior Vice President, Clinical Development and such other duties as are assigned to Executive by the Company’s Chief Executive Officer. Executive’s primary office location shall be the Company’s headquarters located in San Diego, California. Subject to the terms of this Agreement, the Company reserves the right to # reasonably require Executive to perform Executive’s duties at places other than Executive’s primary office location from time to time and to require reasonable business travel, and # modify Executive’s job title and duties as it deems necessary and appropriate in light of the Company’s needs and interests from time to time.

Duties and Location. Executive shall perform such duties as are customarily associated with the position of Executive Vice President and Chief Scientific Officer and such other duties as are assigned to Executive by the CEO. Executive’s primary office location shall be the Company’s headquarters located in San Diego, California. Subject to the terms of this Agreement, the Company reserves the right to reasonably require Executive to perform Executive’s duties at places other than Executive’s primary office location from time to time and to require reasonable business travel.

Duties and Location. Executive shall perform such duties as are customarily associated with the position of Executive Vice President and Chief Medical Officer and such other duties as are assigned to Executive by the CEO. Executive’s primary office location shall be the Company’s headquarters located in San Diego, California. For the Executive’s regular work week, Executive is agreeing to be on-site at the Company’s San Diego, CA headquarters for three (3) consecutive days per week every month unless the Company is closed for the holiday week or the Executive is traveling to another location on a business-related event. In weeks that Executive is traveling to another location on a business-related event, it is still expected that when practicable, Executive will come to the San Diego office for a minimum of two (2) consecutive days per week. It is anticipated that Executive will utilize a Company office in the San Francisco area two (2) days per week. Subject to the terms of this Agreement, the Company reserves the right to reasonably require Executive to perform Executive’s duties at places other than Executive’s primary office location from time to time and to require reasonable business travel.

Duties and Location. Executive shall perform such duties as are customarily associated with the position of Executive Vice President & Chief Financial Officer and such other duties as are assigned to Executive by the CEO. Executive’s primary office location shall be the Company’s headquarters located in San Diego, California. Subject to the terms of this Agreement, the Company reserves the right to reasonably require Executive to perform Executive’s duties at places other than Executive’s primary office location from time to time and to require reasonable business travel.

1.2Duties and Location. Executive will perform such duties as are required by the Company’s Chief Executive Officer to whom Executive will report. Executive’s primary office location will be the Company’s San Diego, California office. The Company reserves the right to reasonably require Executive to perform Executive’s duties at places other than Executive’s primary office location from time to time, and to require reasonable business travel. The Company may modify Executive’s job title and duties as it deems necessary and appropriate in light of the Company’s needs and interests from time to time.