Dispute Escalation. In the event of a Dispute between the Parties, the Parties will first attempt in good faith to resolve such dispute by negotiation and consultation between themselves. In the event that such dispute is not resolved on an informal basis within ​ days from receipt of the written notice of a Dispute, any Party may, by written notice to the other, have such dispute referred to the Executive Officers (or their designees, which designee is required to have decision-making authority on behalf of such Party), who will attempt in good faith to resolve such Dispute by negotiation and consultation for a ​ day period following receipt of such written notice.

Escalation. The Parties hereby agree that during the Term there shall be an escalation of 15% on every 3 years on Warm shell Rent and 12% on every 3 years for Car Park rent. Rent shall co escalate with the Rent Escalation as per Clause 6.4 of the Head Lease Deed. Accordingly the first escalation shall be effective 1st July 2022.

Dispute Resolution; Escalation. Any dispute arising out of or in connection with this Agreement shall be settled, if possible, through good faith negotiations between the Parties. If the Parties are unable to settle such dispute within ​ of first considering such dispute, such dispute shall be referred to the Alliance Managers for resolution. The Alliance Managers of both Parties shall meet to attempt to resolve such dispute. If the Alliance Managers are unable to settle such dispute within ​ of first considering such dispute, such dispute shall be referred to the Executive Officers for resolution. The Executive Officers of both Parties shall meet to attempt to resolve such dispute. Such resolution, if any, of a referred issue shall be final and binding on the Parties. All negotiations pursuant to this [Section 13.6] are confidential and shall be treated as compromise and settlement negotiations for purposes of applicable rules of evidence. If the Executive Officers cannot resolve such dispute within ​ after either Party requests such a meeting in writing, then either Party shall have the right to pursue any and all remedies available at law or equity.

Escalation. If the Parties are unable to resolve any such dispute within thirty (30) days after consultation between responsible counsel of the Parties, a Party may, by written notice to the other Party, have such dispute referred to the respective nominees of the Parties, who shall be senior executives with the authority to resolve such disputes. Such nominees shall attempt to resolve the referred dispute by good faith negotiations within thirty (30) days after such notice is received.

Dispute Resolution; Escalation. The Parties recognize that disputes as to certain matters arising out of or in connection with this Agreement may arise from time to time. It is the objective of the Parties to establish procedures to facilitate the resolution of disputes arising out of or in connection with this Agreement in an expedited manner by mutual cooperation. To accomplish this objective, any and all disputes between the Parties arising out of or in connection with this Agreement (other than # matters within the purview of the JSC, which will be resolved in accordance with Section 5.5 (Decision-Making; Escalation to Senior Officers) and # matters for which this Agreement expressly provides are subject to a Party’s discretion or sole decision-making authority), will first be referred to the Senior Officers for resolution. The Senior Officers will attempt to resolve the matter in good faith. If the Senior Officers fail to resolve such matter within ​ Business Days after the date on which the matter is referred to the Senior Officers (unless a longer period is agreed to by the Parties), then either Party may submit the dispute for final resolution by binding arbitration in accordance with [Section 13.2] (Arbitration).

Uses; Dispute Escalation Process. The Governance Process described in this Section 20 shall be used for negotiations and resolution of disputes and other issues that arise or occur between the parties with respect to the subject matter of this Agreement, and such governance process shall begin reasonably promptly after a request for use of the governance process is provided to the other party (a “Dispute Notice”). Within thirty (30) days after such Dispute Notice, the Level 1 representatives of each party shall meet to discuss the issue. If the Level 1 representatives cannot agree at the meeting to resolve the issue, each party shall reduce to a writing their respective positions and provide the other party with the same no later than fifteen (15) days after such meeting. Within fifteen (15) days after such exchange, or as soon thereafter as can reasonably be scheduled, the Level 2 representatives shall meet to determine whether they can reach an agreement. If they cannot, the issue shall be escalated to the Level 3 representatives of each party, who shall meet as reasonably practicable. Any of the meetings described in this Section 20(c) may be conducted by telephone or such locations as are mutually convenient, including during the governance process meetings set forth above. If the governance process involves consideration of a dispute for which a party, acting in good faith, deems that time is of the essence, each of the preceding periods set forth in this Section 20(c) shall be shortened to address the dispute on such expedited basis as is reasonably practicable.

Dispute Escalation. In the event of a Dispute between the Parties, the Parties will first attempt to resolve such Dispute by negotiation and consultation between themselves. In the event that such Dispute is not resolved on an informal basis within ​ days from receipt of the written notice of a Dispute, any Party may, by written notice to the other, have such Dispute referred to the Executive Officers (or their designee, which designee is required to have decision-making authority on behalf of such Party), who will attempt to resolve such Dispute by negotiation and consultation for a ​ day period following receipt of such written notice.

Escalation. If the Parties are unable to resolve any such dispute within thirty (30) days after consultation between responsible counsel of the Parties, a Party may, by written notice to the other Party, have such dispute referred to the respective nominees of the Parties, who shall be senior executives with the authority to resolve such disputes. Such nominees shall attempt to resolve the referred dispute by good faith negotiations within thirty (30) days after such notice is received.

Dispute Escalation. In the event of a dispute between the Parties arising out of or in connection with this Termination Agreement, the Parties will first attempt in good faith to resolve such dispute by negotiation and consultation between themselves. In the event that such dispute is not resolved on an informal basis within thirty (30) days, any Party may, by written notice to the other, have such dispute referred to each Party’s Chief Executive Officer or his or her designee (who will be a senior executive with the appropriate authority to determine the mater for such Party), who will attempt in good faith to resolve such dispute by negotiation and consultation for a thirty (30) days period following receipt of such written notice.

Escalation. If Vertex has exercised its ​ rights under [Section 10.3.2], and there is a dispute regarding whether CRISPR is in breach of this Agreement ​, either Party may make a written request that ​ be referred for resolution to Executive Officers of each Party (or their designees). Within ​ days after such request, the Executive Officers of each Party (or their designees) will meet in person at a mutually acceptable time and location or by means of telephone or video conference to negotiate a settlement of a ​. Each Party may elect to have such Party’s JAC representatives participate in such meeting, if desired, provided that it provides the other Party with reasonable advance notice of such intent so as to enable the other Party to have its JAC representatives also participate in such meeting, if desired. In the event that the Executive Officers of each Party (or their designees) fail to resolve the ​ within such ​ period the ​ will be referred to mediation under [Section 10.3.3(b)].