Development Target. Zai shall, # within ​ months of the ​, obtain Regulatory Approval for the Licensed Product for the same Indication in the Territory; provided, however, ​, Zai shall obtain Regulatory Approval for the Licensed Product for the same Indication in the Territory within ​ months of the ​; # ​ within ​ months after the Effective Date; and # ​ within # ​ months after ​, or # ​ months after ​ (each such Zai obligation a “Development Target” and each such corresponding deadline a “Development Target Deadline”); provided that each such Development Target Deadline shall be extended by ​ days or such other period of time as agreed in writing by the Parties if # Zai demonstrates to NVCR that Zai has utilized Commercially Reasonable Efforts to achieve the corresponding Development Target by the corresponding Development Target Deadline and # such inability to achieve such Development Target by the corresponding Development Target Deadline is due to # reasons outside of Zai’s control including changes to the regulatory process or Applicable Laws, or delays caused by Governmental Authorities including delays in providing necessary approvals or responses; or # NVCR exercising its final decision making authority with Zai’s objection.

Development Target. Zai shall, # within ​ months of the ​, obtain Regulatory Approval for the Licensed Product for the same Indication in the Territory; provided, however, ​, Zai shall obtain Regulatory Approval for the Licensed Product for the same Indication in the Territory within ​ months of the ​; # ​ within ​ months after the Effective Date; and # ​ within # ​ months after ​, or # ​ months after ​ (each such Zai obligation a “Development Target” and each such corresponding deadline a “Development Target Deadline”); provided that each such Development Target Deadline shall be extended by ​ days or such other period of time as agreed in writing by the Parties if # Zai demonstrates to NVCR that Zai has utilized Commercially Reasonable Efforts to achieve the corresponding Development Target by the corresponding Development Target Deadline and # such inability to achieve such Development Target by the corresponding Development Target Deadline is due to # reasons outside of Zai’s control including changes to the regulatory process or Applicable Laws, or delays caused by Governmental Authorities including delays in providing necessary approvals or responses; or # NVCR exercising its final decision making authority with Zai’s objection.

Development Target. Zai shall, # within ​ months of the ​, obtain Regulatory Approval for the Licensed Product for the same Indication in the Territory; provided, however, ​, Zai shall obtain Regulatory Approval for the Licensed Product for the same Indication in the Territory within ​ months of the ​; # ​ within ​ months after the Effective Date; and # ​ within # ​ months after ​, or # ​ months after ​ (each such Zai obligation a “Development Target” and each such corresponding deadline a “Development Target Deadline”); provided that each such Development Target Deadline shall be extended by ​ days or such other period of time as agreed in writing by the Parties if # Zai demonstrates to NVCR that Zai has utilized Commercially Reasonable Efforts to achieve the corresponding Development Target by the corresponding Development Target Deadline and # such inability to achieve such Development Target by the corresponding Development Target Deadline is due to # reasons outside of Zai’s control including changes to the regulatory process or Applicable Laws, or delays caused by Governmental Authorities including delays in providing necessary approvals or responses; or # NVCR exercising its final decision making authority with Zai’s objection.

Development Target. Zai shall, # within ​ months of the ​, obtain Regulatory Approval for the Licensed Product for the same Indication in the Territory; provided, however, ​, Zai shall obtain Regulatory Approval for the Licensed Product for the same Indication in the Territory within ​ months of the ​; # ​ within ​ months after the Effective Date; and # ​ within # ​ months after ​, or # ​ months after ​ (each such Zai obligation a “Development Target” and each such corresponding deadline a “Development Target Deadline”); provided that each such Development Target Deadline shall be extended by ​ days or such other period of time as agreed in writing by the Parties if # Zai demonstrates to NVCR that Zai has utilized Commercially Reasonable Efforts to achieve the corresponding Development Target by the corresponding Development Target Deadline and # such inability to achieve such Development Target by the corresponding Development Target Deadline is due to # reasons outside of Zai’s control including changes to the regulatory process or Applicable Laws, or delays caused by Governmental Authorities including delays in providing necessary approvals or responses; or # NVCR exercising its final decision making authority with Zai’s objection.

Target. If, upon the conclusion of the Performance Period (or the date of the Change in Control if [Section 1(e)(ii)] of this Exhibit A is applicable), RTSR for the Performance Period equals the target level, as set forth in the Performance Matrices, 100% of the PRSUs will become earned.

Target. If, upon the conclusion of the Performance Period, RTSR for the Performance Period equals the target level, as set forth in the Performance Matrix, 100% of the PRSUs shall become Vested.

Target. If, upon the conclusion of the Performance Period, RTSR for the Performance Period equals the target level, as set forth in the Performance Matrix, 100% of the PRSUs shall become Vested.

Target. If, upon the conclusion of the Performance Period (or the date of the Change in Control if [Section 1(e)(ii)] of this Exhibit A is applicable), RTSR for the Performance Period equals the target level, as set forth in the Performance Matrices, 100% of the PRSUs shall become earned.

Target-by-Target Milestones. It is understood that, subject to [Section 7.4.3(b)], the payments under this [Section 7.4] shall be due only once with respect to each Milestone Target.

Excluded Target. The JSC may not select any Excluded Target as a target or compound to undergo Primary Screen or as a Selected Target or Cardiomyopathy Target Candidate, and [[MyoKardia:Organization]] may not select an Excluded Target as a Cardiomyopathy Target. For clarity, # Fulcrum will not be required to provide any information regarding any Excluded Targets to [[MyoKardia:Organization]], conduct target validation activities on such Excluded Target or to include any information with respect to such Excluded Target in any Data Package and # [[MyoKardia:Organization]] will have no payment obligations to Fulcrum with respect to any Excluded Targets. For further clarity, # if such target qualifies as an Excluded Target solely pursuant to [Section 1.62(a)(ii)] (Excluded Target), Fulcrum may notify [[MyoKardia:Organization]] in writing of Fulcrum’s election, in its sole discretion, not to exclude such target from this Agreement, or # if such target qualifies as an Excluded Target solely pursuant to [Section 1.62(a)(i)] (Excluded Target) and the applicable license, option or other grant of rights is non-exclusive, Fulcrum shall provide written notice of the nature of such license, option or grant of rights (subject to obligations of confidentiality to any Third Party) and, upon [[MyoKardia:Organization]]’s written notice to Fulcrum, such target will no longer constitute an Excluded Target, and if [[MyoKardia:Organization]] designates such target as a Cardiomyopathy Target, the scope of the grant of rights with respect to such target to [[MyoKardia:Organization]] under this Agreement will be reduced solely to the extent necessary to comply with the applicable license, option or other grant of rights.