In accordance with the terms and conditions of this Agreement, upon the achievement of each of the following milestones set forth below for ​Products developed by or on behalf of Licensee, its Affiliates, or its or their sublicensees (as applicable), the corresponding one-time milestone payment will be due to MSD, ​:

Development and Regulatory Milestones. With respect to each of the milestone events set forth in [Section 8.6.1 and 8.6.2]2], the Party that achieved such milestone event and with respect to each of the milestone events set forth in [Section 8.6.3], Roche shall inform the other Party or Poseida, as applicable, within ​ following the achievement of such event. Roche shall pay Poseida the respective milestone payment payable pursuant to [Section 8.6] for achievement of such milestone event within ​ of receipt of an undisputed invoice from Poseida with respect thereto after achievement of such milestone event.

Tier 1 Programs; Optioned Tier 2 Programs. For each Tier 1 Program or Optioned Tier 2 Program, Roche shall pay Poseida each applicable non-creditable, non-refundable milestone payment set forth in the following table, in accordance with [Section 9.1.1], following the first achievement of the corresponding milestone event for such Tier 1 Program or Optioned Tier 2 Program, as applicable:

Development Milestones. Catalyst agrees to pay Mosaic upon the occurrence of each of the following milestones ​ achieved by Catalyst or its Affiliates (but not, for clarity, by any Sublicensees) with respect to each Product, on a Product-by-Product and Indication-by-Indication basis, in accordance with this Section 10.1, provided, that at the time any such development milestone is achieved, that Catalyst is responsible for the development or regulatory activity with respect to such Product triggering such milestone. ​.

Development and Regulatory Milestones. Subject to the remainder of this Section 6.4, Anteris shall pay to vTv the one-time, non-refundable, non-creditable milestone payments set forth in the table below upon the first achievement of the applicable milestone event by the first Licensed Product (whether by or on behalf of Anteris or its Affiliates or Sublicensees):

Development and Regulatory Milestones. In partial consideration of the obligations imposed on REGENX and rights granted to PARTNER hereunder and under the Penn Sublicense Agreement, PARTNER shall pay to REGENX the following one-time payments within ​ after the achievement of each of the following milestone events by or on behalf of the Parties, any of their Affiliates or any Sublicensee in activities under this Agreement during the Term with respect to the applicable Licensed Product for use in the Licensed Field, which shall be nonrefundable, non-creditable and fully earned upon the achievement of the applicable milestone event:

In partial consideration for the amendment and restatement of the Prior Agreement and the rights and licenses granted to [[EPIZYME:Organization]] hereunder, [[EPIZYME:Organization]] shall make the non-creditable milestone payments to EISAI that are set forth below in accordance with [Section 6.3.2] upon the first occurrence of the milestone events set forth below.

Development and Regulatory Milestones. Ono shall notify [[Forty Seven:Organization]] in writing within ​ after the first achievement by a Product of the applicable milestone event below (whether by Ono or its Affiliate or Sublicensee). Ono shall pay to [[Forty Seven:Organization]] the one-time, non-refundable, non-creditable payment for such milestone event set forth in the table below within ​ of receipt by Ono of [[Forty Seven:Organization]]’s invoice for such milestone payment. For the avoidance of doubt, each of the following milestone payments shall be payable only once regardless of the number of times achieved by one or more Products.

Development and Regulatory Milestones. Licensee shall pay [[AstraZeneca:Organization]] each of the following non-refundable, non-creditable milestone payments upon the first achievement of the corresponding Milestone Event as set forth below in accordance with Section 4.3.2:

Development and Regulatory Milestones. As partial consideration for the exclusive rights and covenants granted by Poseida to Takeda pursuant to this Agreement, Takeda shall make non-refundable, non-creditable milestone payments (each, a “Development and Regulatory Milestone Payment”) to Poseida upon achievement of the milestones set forth below (each, a “Development and Regulatory Milestone”) on a Program-by-Program basis. Takeda will notify Poseida of the achievement of each Development and Regulatory Milestone no later than […​…] after Takeda becoming aware of the achievement thereof. Thereafter, Poseida will provide Takeda with an invoice for the corresponding Development and Regulatory Milestone Payment, and Takeda will pay to Poseida such Development and Regulatory Milestone Payment no later than […​…] after receipt by Takeda thereof.