Preliminary Total Development Cost Estimate. Based upon the ​’s Work described in [Schedule 1] and the ​ Improvement Allowance (defined below) for the ​ Improvements, ​ has prepared an estimate of the Total Development Costs (as defined in Exhibit J) for the Premises (the “Preliminary Total Development Cost Estimate”), which is set forth on [Schedule 3] attached hereto and includes detailed hard and soft cost budgets for the ​’s Work and the ​ Improvement Allowance.

Cost . The cost to design, permit and construct the Tenant Improvements shall be paid by Landlord. Any and all costs, fees or expenses of any kind or nature that are incurred due to changes requested by Tenant shall be the sole responsibility of Tenant.

CD Total Development Cost Estimate............................................................................ Exhibit B

Through the 5,003 Expansion Premises Commencement Date, ​ shall continue to pay ​’s Proportionate Share of the Insurance Cost in accordance with the provisions of the Original Lease, specifically including, without limitation, the provisions of Paragraph 59(g) thereof.

Increased Cost. [Section 6.4] to the Repurchase Agreement is amended and restated in its entirety to read as follows:

Increased Cost. If any Change in Law subsequent to the Effective Date:

CONVERSION COST. [[Organization B:Organization]] agrees to reimburse [[Organization A:Organization]]’s certificate processing cost by adding $1,500 to the Principal for each note conversion of at least $150,000 effected by [[Organization A:Organization]]. If the conversion is for less than that amount, [[Organization A:Organization]] shall be responsible for any costs.

Cost Pools. Landlord shall have the right, from time to time, to equitably allocate some or all of the Direct Expenses for the Project among different portions or occupants of the Project (the " XE "Cost Pools" Cost Pools"), in Landlord's reasonable discretion. Such Cost Pools may include, but shall not be limited to, the office space tenants of a building of the Project or of the Project, and the laboratory space tenants of a building of the Project or of the Project. The Direct Expenses within each such Cost Pool shall be allocated and charged to the tenants within such Cost Pool in an equitable manner.

Cost of Collection. If default is made in the payment of this Note, the Borrower shall pay the Holder hereof costs of collection, including reasonable attorneys’ fees.

As consideration for performance under the terms of this Agreement, [[Organization B:Organization]] shall pay the [[Organization A:Organization]] in accordance with the attached budget ([Exhibit A]). All costs outlined in the budget shall remain firm for the duration of the Study, unless otherwise agreed in writing by the [[Organization A:Organization]] and [[Organization B:Organization]]. Payments are not refundable. If not budgeted, the clinical trial EC/IRB review fee will be paid by [[Organization B:Organization]] directly to the IEC/RB.