Position. Executive shall serve as the Company’s Executive Vice President & Chief Financial Officer, reporting to [[Person B:Person]], the Company’s President & CEO (the “CEO”). Executive’s commencement of employment with the Company will be on or before July 28, 2021 (such actual date of commencement of employment with the Company, the “Start Date”). During the term of Executive’s employment with the Company, Executive will devote Executive’s best efforts and substantially all of Executive’s business time and attention to the business of the Company, except for approved vacation periods and reasonable periods of illness or other incapacities permitted by the Company’s general employment policies.

Position. Executive shall serve as Executive Vice President and Chief Scientific Officer of the Company, reporting to [[Person A:Person]], the Company’s President & CEO (the “CEO”). Executive’s commencement of employment with the Company will be on or before March 2, 2020 (such actual date of commencement of employment with the Company, the “Start Date”). During the term of Executive’s employment with the Company, Executive will devote Executive’s best efforts and substantially all of Executive’s business time and attention to the business of the Company, except for approved vacation periods and reasonable periods of illness or other incapacities permitted by the Company’s general employment policies.

Position. Executive shall serve as the Company’s Executive Vice President and Chief Medical Officer, reporting to [[Person A:Person]], the Company’s President & CEO (the “CEO”). Executive’s commencement of employment with the Company will be on or before December 2, 2019 (such actual date of commencement of employment with the Company, the “Start Date”). During the term of Executive’s employment with the Company, Executive will devote Executive’s best efforts and substantially all of Executive’s business time and attention to the business of the Company, except for approved vacation periods and reasonable periods of illness or other incapacities permitted by the Company’s general employment policies.

Appointment. Executive’s start date was March 26, 2018 (the “Start Date”). Executive shall serve as Chief Financial Officer, reporting to the Chief Executive Officer. As Chief Financial Officer, Executive shall perform the duties that are consistent with such position and that may be assigned to Executive by the Company from time to time. During Executive’s employment with the Company, Executive shall # devote substantially all of Executive’s business efforts to the Company, and # faithfully and to the best of Executive’s abilities and experience, and in accordance with the standards and ethics of the business in which the Company is engaged, perform all duties that may be required of Executive by this Agreement, the Company’s policies and procedures, and such other duties and responsibilities as may be assigned to Executive from time to time, as well as the directives of the Board. During Executive’s employment with the Company, Executive shall not engage in any activity that conflicts with or is detrimental to the Company’s best interests, as determined by the Board or Chief Executive Officer.

Positions and Duties. The Company hereby agrees to employ Executive, as its Chief Financial Officer, and Executive hereby agrees to serve the Company in such capacity, during the Employment Term. Subject to Executive’s acceptance of the terms in this Agreement, Executive’s anticipated start date is January 11, 2021 or such other date as may be reasonably agreed upon with the Company’s President and Chief Executive Officer (the “CEO”, and the date Executive actually begins employment with the Company, the “Start Date”). Executive will render such business and professional services in the performance of her duties, consistent with Executive’s position within the Company, as will reasonably be assigned to Executive by the Company’s CEO . The period of Executive’s employment under this Agreement is referred to herein as the “Employment Term.”

Position. Executive will serve as the Chief Financial Officer and Chief Business Officer of the Company. During the term of Executive’s employment with the Company, Executive will devote Executive’s best efforts and substantially all of Executive’s business time and attention to the business of the Company, except for approved vacation periods and reasonable periods of illness or other incapacities permitted by the Company’s general employment policies.

Appointment. Executive’s start date with the Company is July 13, 2020 or such other date as mutually agreed upon by the Company and Executive (the “Start Date”). Executive shall serve as Chief Financial Officer, reporting to the President and Chief Operating Officer. As Chief Financial Officer, Executive will have such duties and responsibilities typically associated with such officer plus other reasonable duties as may from time to time be assigned to Executive. During Executive’s employment with the Company, Executive shall # devote substantially all of Executive’s business efforts to the Company provided, however, that Executive may # participate in charitable, civic, educational, professional, community or industry affairs, and # serve as a board member, advisor or a similar position, of up to two other companies, so long as such service does not conflict with or is not detrimental to the Company’s best interests, as determined in good faith by the Board, and # faithfully and to the best of Executive’s abilities and experience, and in accordance with the standards and ethics of the business in which the Company is engaged, perform all duties that may be required of Executive by this Agreement, the Company’s policies and procedures, and such other duties and responsibilities as may be assigned to Executive from time to time, as well as the directives of the Board. During Executive’s employment with the Company, Executive shall not engage in any activity that conflicts with or is detrimental to the Company’s best interests, as determined by the Board. Executive and the Company acknowledge that Executive’s primary office will be located at the Company’s New York, NY office, but that Executive will be required to spend a certain amount of time each month at the Company’s Waltham, MA headquarters.

Position. Executive shall serve as the Company’s Chief Financial Officer. During the term of Executive’s employment with the Company, Executive will devote Executive’s best efforts and substantially all of Executive’s business time and attention to the business of the Company.