Audited Financial Statements. The Audited Financial Statements # were prepared in accordance with GAAP consistently applied throughout the period covered thereby, except as otherwise expressly noted therein; # fairly present the financial condition of the Borrower and its Subsidiaries as of the date thereof and their results of operations, cash flows and changes in Shareholders’ Equity for the period covered thereby in accordance with GAAP consistently applied throughout the period covered thereby, except as otherwise expressly noted therein; and # show all material indebtedness and other liabilities, direct or contingent, of the Borrower and its Subsidiaries as of the date thereof, including liabilities for taxes, material commitments and Indebtedness.

Audited Financial Statements. As soon as available, but in any event within ninety (90) days after the end of each fiscal year of the Borrower (or, if earlier, fifteen (15) days after the date required to be filed with the SEC (without giving effect to any extension permitted by the SEC))(commencing with the fiscal year ended ​), a Consolidated and consolidating balance sheet of the Borrower and its Subsidiaries as at the end of such fiscal year, and the related Consolidated and consolidating statements of income or operations, changes in Shareholders’ Equity and cash flows for such fiscal year, setting forth in each case in comparative form the figures for the previous fiscal year, all in reasonable detail and prepared in accordance with GAAP, # such Consolidated statements to be audited and accompanied by a report and opinion of an independent certified public accountant of nationally recognized standing reasonably acceptable to the Administrative Agent, which report and opinion shall be prepared in accordance with generally accepted auditing standards and shall not be subject to any “going concern” or like qualification or exception or any qualification or exception as to the scope of such audit, and # such consolidating statements to be certified by the chief executive officer, chief financial officer, treasurer or controller that is a Responsible Officer of the Borrower to the effect that such statements are fairly stated in all material respects when considered in relation to the Consolidated financial statements of the Borrower and its Subsidiaries.

Annual Audited Financial Statements. (i) To the extent the Borrower’s Board of Directors does not require an audit, as soon as available, but no later than thirty (30) days after the last day of Borrower’s fiscal year, Borrower prepared financial statements prepared under GAAP, consistently applied, and # if required by Borrower’s Board of Directors, as soon as available, but no later than one hundred eighty (180) days after the last day of Borrower’s fiscal year, audited consolidated financial statements prepared under GAAP, consistently applied, together with an unqualified opinion (other than as to going concern for venture backed companies similar to Borrower or a qualification resulting solely from the scheduled maturity of the Credit Extensions made hereunder occurring within one year from the time such opinion is delivered) on the financial statements from Ernst & Young, any other “Big Four” accounting firm, or any other independent certified public accounting firm reasonably acceptable to Bank;

fairly present the financial condition of the Borrowers and their Subsidiaries, as applicable, as of the dates thereof and its results of operations for the period covered thereby in accordance with GAAP consistently applied throughout the periods covered thereby, subject, in the case of the Unaudited Financial Statements, to normal year-end audit adjustments and the absence of footnotes; and

Financial Statements. The Borrower has heretofore delivered to the ​ the audited consolidated statement of assets and liabilities and statements of operations, changes in net assets and cash flows of the Borrower and its Subsidiaries as of and for the fiscal year ended ​, reported on by Deloitte & Touche LLP, independent public accountants, in the form of the report of the Borrower to the SEC on Form 10-K for such year, which financial statements present fairly, in all material respects, the consolidated financial position and results of operations and cash flows of the Borrower and its Subsidiaries as of such date and for such period in accordance with GAAP.

Financial Statements. The audited consolidated financial statements of Regional (excluding a Special Purpose Subsidiary) for the fiscal year ending ​, are true and correct in all material respects and have been prepared in accordance with GAAP, consistently applied (except for changes in application in which Borrowers’ accountants concur) and present fairly in all material respects the financial position of Regional and its Subsidiaries as of such dates and the results of their operations for such periods. Since the date of the most recent financial statements delivered pursuant to this Agreement, no Material Adverse Effect has occurred.

Financial Statements. Deliver to the Administrative Agent for further distribution to each Lender:

The consolidated balance sheet of the Company and its Consolidated Subsidiaries as at December 31, 20122015 and the related consolidated statements of income and cash flows of the Company and its Consolidated Subsidiaries for the fiscal year then ended, certified by PriceWaterhouseCoopers, LLP, certified public accountants, and set forth in the Company’s 20122015 Form 10-K, a copy of which has been delivered to each of the Lenders, fairly present, in all material respects, in conformity with GAAP, the consolidated financial position of the

Financial Statements. The Company will deliver, or cause to be delivered, to each of the Lenders:

Financial Statements. The Operating Company shall provide to PureTech and PTH PLC such financial and other information as reasonably determined by PureTech or PTH plc to be necessary or appropriate in the preparation of PTH plc’s Accounts. Such information shall be provided in a manner and at such times as PureTech or PTH PLC shall require in their sole and absolute discretion.

#​ has provided to the Companies the audited annual financial statements of ​ for the fiscal year ended December 31, 2016 (the “​ Financial Statements”) and will, prior to Closing, provide to the Companies intervening quarterly unaudited financial statements (the “​ Quarterly Statements”), including a balance sheet and profit and loss statement.

Financial Statements. As soon as available and in any event within ten (10) Business Days after the end of each month prior to the Closing Date, ​ shall deliver to the Bank such of its balance sheets and statements of operations with respect to ​ as are internally prepared by it in the Ordinary Course of Business.

Financial Statements. The Rights Agreement is hereby amended such that number “150” as it appears in [Section 4.2(a)] thereof is hereby deleted and replaced with the number “180,” and such that the number “45” as it appears in [Section 4.2(b)] thereof is hereby deleted and replaced with the number “60.”

Deliver to the Administrative Agent, which in turn will make them available to the ​, in form and detail satisfactory to the Administrative Agent and the Required ​:

Financial Statements. Receipt and satisfactory review by the Lenders of the consolidated financial statements of the Borrower and its Subsidiaries for the fiscal years ended 2016, 2015 and 2014, including balance sheets, income and cash flow statements audited by

The Financial Statements attached to [Schedule 4.1.11(a)] present fairly in all material respects the financial position of the Company as of the dates designated therein and the results of operations and cash flows for the periods designated therein, and were prepared in accordance with GAAP, subject, in the case of the interim monthly financial statements, to normal recurring year-end adjustments and the absence of footnotes.

Financial Statements. Attached hereto as [Schedule 4.2(j)] are copies of the following unaudited financial statements with respect to the Seller Business (collectively “Seller’s Financial Statements”): # balance sheet of Seller as at December 31, 2015 (the "Balance Sheet") and for the quarter ending March 31, 2016 (the "Interim Balance Sheet"), together with the related statement of revenues and expenses for the 12 month period then ended, and # income statements of Seller for the twelve months ending December 31, 2015 and for the quarter ending March 31, 2016. Seller’s Financial Statements: # are true and complete in all material respects; # have been prepared in accordance with the books and records of Seller; # have been prepared in accordance with generally accepted accounting principles (“GAAP”) applied on a basis consistent with prior periods; and # present fairly in all material respects the financial condition of Seller as of the dates and for the periods indicated. Seller has no outstanding Indebtedness, except for current liabilities reflected in the Final Net Working Capital.