Agreement Term. This Agreement shall commence on the Effective Date and shall continue, unless sooner terminated in accordance with this Agreement, until September 30, 2020 (the “Initial Period”); provided, however, this Agreement will automatically renew for successive one year renewal terms (each a "Renewal Period" and together with the Initial Period, the “Agreement Period”) unless either party notifies the other party in writing at least ninety (90) days prior to expiration of the Initial Period or any Renewal Period. During the Agreement Period, Executive’s employment may be terminated by the Company with or without Cause, subject to the provisions of Section 6 of this Agreement, and Executive may resign or otherwise terminate his employment with the Company at any time, with or without notice. Notwithstanding the provisions of this Section, the provisions of Sections 8, 9, 10, 11, 12 and 13 shall survive the termination of Executive’s employment (for any reason) and remain in full force and effect thereafter.

Agreement (Term). [Section XI].A of the Agreement is hereby amended and restated in its entirety to read as follows:

AGREEMENT TERM. The definition of “Initial Term” in Section 1 of the Agreement is hereby deleted in its entirety and replaced with the following:

Agreement Term. The term of this Agreement will commence as of the Effective Date and, unless earlier terminated in its entirety in accordance with Section 9.2 (Early Termination) or by mutual written consent, will continue in effect until the expiration of the last possible Royalty Term under this Agreement. The time between the Effective Date and termination of this Agreement in its entirety for any reason is the “Term”.

Agreement Term. Unless terminated earlier in accordance with this Article XV, on a Program-by-Program basis, the term of this Agreement (the “Term”) shall commence on the Effective Date and shall expire upon the expiration of the Royalty Term for any Licensed Product sold hereunder.

Term of Agreement. The term of this Agreement (the “Term”) will commence on the Effective Date and continue until expiration of the later of expiration or termination of all payment obligations of Ono accruing prior to the effective date of early termination under this Agreement or expiration of the Royalty Term for all Products licensed hereunder, unless earlier terminated as provided below.

Term of Agreement. This Agreement shall commence on the date hereof and continue in effect until the earlier of # the Executive’s Separation from Service other than within twenty-four (24) months following a Change in Control (each as defined below); # the Company’s satisfaction of all of its obligations under this Agreement; or # the execution of a written agreement between the Company and Executive terminating this Agreement.

Term of Agreement. This Agreement shall be effective upon the execution by the parties, and shall remain in effect until the date Executive’s employment by the Company is terminated; provided, however, that if Executive experiences an Involuntary Termination of Employment, the term shall continue in effect until all payments and benefits have been made or provided to Executive under this Agreement.

Term of Agreement. This Agreement was originally effective commencing on June 1, 2002 (the original effective date of this Agreement). This Agreement shall, as of its first anniversary, and on each annual anniversary thereof, be extended automatically, without further action by the Employee or the Company, for an additional one year, so that there shall, as of June 1 of each year, be one year remaining in the term of this Agreement (the "Employment Period"), unless the Company gives written notice to the Employee of its decision to not renew the Agreement at least 30 days prior to the applicable anniversary date and subject to earlier termination as otherwise hereinafter provided. The amendment and restatement of this Agreement is effective September 7, 2018 (the “Effective Date”).

Term of Agreement. This Agreement will have an initial term commencing on the Effective Date and ending on the third anniversary of the Effective Date (the “Initial Term”). At the end of the Initial Term (and at the end of each Additional Term), this Agreement will renew automatically for an additional three (3) year term (each an “Additional Term”), unless either Executive or the Company provides the other party with written notice of non-renewal at least sixty (60) days prior to the date of automatic renewal. A non-renewal by the Company shall be deemed a termination without Cause unless the Company and the Executive agree in writing otherwise. If Executive becomes entitled to benefits under Section 3 during the term of this Agreement, the Agreement will not terminate until all of the obligations of the parties hereto with respect to this Agreement have been satisfied. Executive shall be entitled to benefits under Section 3 only once and this Agreement will terminate once all of the obligations of the parties hereto with respect to this Agreement have been satisfied.