Agent’s Review of Proposed Amendments and Supplements. Prior to amending or supplementing the Registration Statement (including any registration statement filed under Rule 462(b) under the Securities Act) or the Prospectus (excluding any amendment or supplement through incorporation of any report filed under the Exchange Act), the Company shall furnish to the Agent for review, a reasonable amount of time prior to the proposed time of filing or use thereof, a copy of each such proposed amendment or supplement, and the Company shall not file or use any such proposed amendment or supplement without the Agent’s prior consent, which shall not be unreasonably withheld, conditioned or delayed, and shall file with the Commission within the applicable period specified in Rule 424(b) under the Securities Act any prospectus required to be filed pursuant to such Rule.

Supplements and Amendments. The Company and Warrant Holder may from time to time supplement or amend this Warrant Agreement in order to cure any ambiguity, to correct or supplement any provision contained herein which may be defective or inconsistent with any provisions herein, or to make any other provisions in regard to matters or questions arising hereunder which Company and Warrant Holder may deem necessary or desirable. Any and all amendments and supplements shall be in writing and signed by the Parties.

Supplements and Amendments. Company and Grantee may from time to time supplement or amend this Option Agreement in order to cure any ambiguity, to correct or supplement any provision contained herein which may be defective or inconsistent with any provisions herein, or to make any other provisions in regard to matters or questions arising hereunder which Company and Grantee may deem necessary or desirable. Any and all amendments and supplements shall be in writing and signed by the Parties.

Copy of Amendments, Supplements. To make no amendment or any supplement to the Prospectus unless MP Securities is given a copy of such proposed amendment or supplement; to advise MP Securities, promptly after it receives notice thereof, of the issuance by any state, federal or other regulatory authority of any stop order or of any order preventing or suspending the use of any Prospectus, of the suspension of the qualification of the Notes for offering or sale in any jurisdiction, of the initiation or threatening of any proceeding for any such purpose, or of any request by any regulatory authority for the amending or supplementing of the Prospectus or for additional information; and, in the event of the issuance of any stop order or of any order preventing or suspending the use of the Prospectus or suspending any such qualification, promptly to use its best efforts to obtain the withdrawal of such order;

Supplements. Notwithstanding anything to the contrary contained herein, [[Organization A:Organization]] may enter into any Supplement providing for the issuance of one or more Series of Additional Notes consistent with, and in compliance with, [Sections 2.2 and 4.15] hereof without obtaining the consent of any holder of any other Series of Notes.

review the Registration Statement and all amendments and supplements thereto a reasonable period of time (but not

review, approve any proposed amendments to, and monitoring execution of the Development Plan;

Supplements and Amendments; Whole Agreement. This Warrant may be amended or supplemented only by an instrument in writing signed by the parties hereto. This Warrant, together with the Purchase Agreement, contains the full understanding of the parties hereto with respect to the subject matter hereof and thereof and there are no representations, warranties, agreements or understandings with respect to the subject matter hereof and thereof other than as expressly contained herein and therein.

Amendments to Registration Statement; Prospectus Supplements. Except as provided in this Agreement and other than periodic and current reports required to be filed pursuant to the Exchange Act, ​ shall not file with the SEC any amendment to the Registration Statement or any supplement to the Base Prospectus that refers to ​, the Transaction Documents or the transactions contemplated thereby (including, without limitation, any Prospectus Supplement filed in connection with the transactions contemplated by the Transaction Documents), in each case with respect to which # ​ shall not previously have been advised and afforded the opportunity to review and comment thereon at least two (2) Business Days prior to filing with the SEC, # ​ shall not have given due consideration to any comments thereon received from ​ or its counsel, or # ​ shall reasonably object, unless ​ reasonably has determined that it is necessary to amend the Registration Statement or make any supplement to the Prospectus to comply with the Securities Act or any other applicable law or regulation, in which case ​ shall promptly (but in no event later than 24 hours) so inform ​, ​ shall be provided with a reasonable opportunity to review and comment upon any disclosure referring to ​, the Transaction Documents or the transactions contemplated thereby, as applicable, and ​ shall expeditiously furnish to ​ a copy thereof. In addition, for so long as, in the reasonable opinion of counsel for ​, the Prospectus is required to be delivered in connection with any acquisition or sale of Purchase Shares by ​, ​ shall not file any Prospectus Supplement with respect to the Purchase Shares without furnishing to ​ as many copies of such Prospectus Supplement, together with the Prospectus, as ​ may reasonably request.

Agent’s Liens. If any Loan Document that purports to create a Lien shall fail or cease to create, except to the extent permitted by the terms of any such Loan Document, a valid and perfected Lien on the Assets covered thereby and, except to the extent permitted by the terms hereof or thereof, a first priority Lien on the Assets covered thereby (in each case, for any reason other than the failure of Agent to take any action within its control); provided that the foregoing parenthetical shall not be applicable with respect to any Assets # to the extent that Agent’s Lien thereon would be perfected by the filing of a uniform commercial code financing statement in the applicable jurisdiction, # to the extent that such Assets consist of Deposit Accounts or Securities Accounts (or Assets held in such Deposit Accounts or Securities Accounts) or # to the extent that the fair market value of all Collateral of any Loan Party that are not subject to a valid and perfected Lien and, except to the extent permitted by the terms hereof or thereof, a first priority Lien, is greater than $250,000 in the aggregate; and

To prepare responses to any comments issued by the staff of the SEC with respect to the General Form for Registration of Securities on Form 10 (the “Form 10”) covering the registration of QSHI’s class of Common Stock, pursuant to Section 12(g) of the Exchange Act, which was filed with the SEC on January 10, 2019. The costs and expenses of the preparation and filing of any amendments or supplements to the Form 10 and any response letters to the SEC shall be borne solely by the Seller. The Seller shall permit the Purchaser’s legal counsel to review and comment on all amendments and supplements to the Form 10, and any response letters related thereto, within a reasonable number of days prior to their filing with the SEC. The Seller hereby agrees to not file any amendment or supplement to the Form 10 or any response letter in a form to which the Purchaser, or its legal counsel, reasonably objects.

Section # References to Agreements, Laws, Etc. Unless otherwise expressly provided herein, # references to Organizational Documents, agreements (including the Loan Documents) and other contractual instruments shall be deemed to include all subsequent amendments, restatements, extensions, supplements and other modifications thereto, but only to the extent that such amendments, restatements, extensions, supplements and other modifications are permitted by the Loan Documents; and # references to any Law shall include all statutory and regulatory provisions consolidating, amending, replacing, supplementing or interpreting such Law.

By signing below, the undersigned consents to the disclosure of the information contained herein in its answers to Items 1 through 5 and the inclusion of such information in the Registration Statement and the related prospectus and any amendments or supplements thereto. The undersigned understands that such information will be relied upon by ​ in connection with the preparation or amendment of the Registration Statement and the related prospectus and any amendments or supplements thereto.

Agent’s Reimbursement and Indemnification. The ​ agree to reimburse and indemnify the Agent ratably in proportion to their respective Commitments (or, if the Commitments have been terminated, in proportion to their Commitments immediately prior to such termination) # for any amounts not reimbursed by ​ for which the Agent is entitled to reimbursement by ​ under the Loan Documents, # for any other expenses incurred by the Agent on behalf of the ​, in connection with the preparation, execution, delivery, administration and enforcement of the Loan Documents (including for any expenses incurred by the Agent in connection with any dispute between the Agent and any Lender or between two or more of the ​) and # for any liabilities, obligations, losses, damages, penalties, actions, judgments, suits, costs, expenses or disbursements of any kind and nature whatsoever which may be imposed on, incurred by or asserted against the Agent in any way relating to or arising out of the Loan Documents or any document delivered in connection therewith or the transactions contemplated thereby (including for any such amounts incurred by or asserted against the Agent in connection with any dispute between the Agent and any Lender or between two or more of the ​), or the enforcement of any of the terms of the Loan Documents or of any such other documents, provided that # no Lender shall be liable for any of the foregoing to the extent any of the foregoing is found in a final non-appealable judgment by a court of competent jurisdiction to have resulted from the gross negligence or willful misconduct of the Agent and # any indemnification required pursuant to [Section 3.5(g)] shall, notwithstanding the provisions of this [Section 10.8], be paid by the relevant Lender in accordance with the provisions thereof. The obligations of the ​ under this [Section 10.8] shall survive payment of the Obligations and termination of this Agreement.

A supplemental indenture to the Existing Secured Note Indenture shall be executed by the Trustee, the Company and the other parties thereto promptly after the requisite consents for the Proposed Amendments under the Existing Secured Indenture are received, but the Proposed Amendments shall not be operative until a Secured Exchange Settlement Date has occurred.

“Agreement” means this Agreement, and all the exhibits, Schedules and other documents attached to or referred to in this Agreement, and all amendments and supplements, if any, to this Agreement.

in the case of any Core Portfolio Investment that is not solely held by the Borrower and/or its Subsidiaries, the terms and conditions of such Core Portfolio Investment provide the Borrower (and/or its Subsidiary, as applicable) with the right to vote to approve or deny any amendments, supplements, waivers or other modifications of such terms and conditions (other than such routine amendments, supplements, waivers or other modifications as are permitted to be approved by the administrative agent only without the vote of the syndicate members);

Prior to the date of this Agreement, true and complete copies of each Material Contract (including all material supplements and amendments thereto) have been made available by the Company to Buyer.

Applications, supplements and amendments, pre- and post- approvals, and labeling approvals) of any Regulatory Authority, necessary to Exploit pharmaceutical product in a regulatory jurisdiction, including Marketing Approval but excluding Price Approval.

Following the Closing Date, the ​ may propose, and the [[Organization A:Organization]] shall review and consider in good faith, one or more amendments to this Agreement pursuant to which the [[Organization A:Organization]] shall reinsure its applicable Quota Share of other product types and/or riders or endorsements to the Reinsured Policies as so proposed by the ​, in each case subject to the same terms and conditions of this Agreement unless otherwise agreed by the parties hereto. Following any such amendments, such other product types and/or riders or endorsements to the Reinsured Policies will constitute “Reinsured Policies” for all purposes of this Agreement.